The Effect of Household-based Screening on Blood Pressure Changes in South Africa: a Regression Discontinuity Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 3,986
- 主要终点
- Nine-year change in systolic blood pressure
研究概览
简要总结
This study will evaluate the effect of household-based screening and care encouragement for blood pressure on subsequent changes in blood pressure. The study uses a quasi-experimental regression discontinuity design with existing population-based secondary data from the 2008, 2010, 2012, 2014, and 2017 waves of the National Income Dynamics Study in South Africa.
详细描述
Household-based screening and referral to care for blood pressure may improve blood pressure control at the population level in many low- and middle-income countries.
This observational study will use a quasi-experimental regression discontinuity design to evaluate the effect of household-based screening for blood pressure with care encouragement for potentially hypertensive individuals on subsequent changes in blood pressure over time.
Individuals had their blood pressure measured in the household as part of the National Income Dynamics Study data collection. If individuals had a measured blood pressure in the hypertensive zone, they were told that they had elevated blood pressure, that high blood pressure can lead to life threatening consequences, and that they should seek further care. The study exploits the fact that individuals were given this information based on a hard blood pressure cutoff. Therefore, the investigators will evaluate the causal effect of this household-based intervention in the absence of randomization by comparing individuals with a baseline blood pressure just above and below the cut off.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 30 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age greater than or equal to 30
- •Valid blood pressure measurements
排除标准
- •Prior diagnosis of hypertension
- •Currently taking medication for blood pressure
- •Measured with a blood pressure above 140 mmHg systolic or 90 mmHg diastolic in a previous wave of data
结局指标
主要结局
Nine-year change in systolic blood pressure
时间窗: Baseline in 2008 and approximately nine years later in 2017.
For each survey wave, blood pressure is measured at the household by a trained enumerator using an electronic blood pressure device. The enumerators take two separate measurements during the course of the visit with at least three minutes between measurements with individuals in a seated position. The investigators will take the average of the two systolic blood pressure measurements as their main outcome measure.
Two-year change in systolic blood pressure
时间窗: Approximately two years based on the difference between survey waves in the years 2008, 2010, 2012, 2014, and 2017
For each survey wave, blood pressure is measured at the household by a trained enumerator using an electronic blood pressure device. The enumerators take two separate measurements during the course of the visit with at least three minutes between measurements with individuals in a seated position. The investigators will take the average of the two systolic blood pressure measurements as their main outcome measure.
次要结局
- Blood pressure treatment(Cross-sectionally in 2010, 2012, 2014, and 2018)
- Health-seeking behavior(Cross-sectionally in 2010, 2012, 2014, and 2018)
研究者
Till Bärnighausen
Alexander von Humboldt University Professor
University Hospital Heidelberg