Validity, reproducibility and responsiveness of the two minute step test in frail cardiac patients
Recruiting
- Conditions
- Aorta Valve Replacementfrailty10046973
- Registration Number
- NL-OMON49400
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 68
Inclusion Criteria
Undergo a Transcatheter Aortic Valve Implantation (TAVI) in the AUMC
Age >= 70 years
Able to walk prior to TAVI (immobility due to aortic stenosis excepted)
Absence of any comorbid disease leading to inability to walk.
Eligible and motivated to participate in cardiac rehabilitation
Exclusion Criteria
Unstable ischemic heart disease
Inability or any contra-indication to perform physical exercise
Life expectancy < 6 months
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Validity of 2MST: Intraclass correlation coefficient (ICC) between VO2-peak<br /><br>CPET and VO2-peak 2MST<br /><br><br /><br>Reproducibility of 2MST: ICC between NoS T1 and NoS T2, and between VO2-peak T1<br /><br>and VO2-peak T2<br /><br><br /><br>Responsiveness of 2MST: minimal clinically important difference (MCID) for NoS<br /><br>T3. </p><br>
- Secondary Outcome Measures
Name Time Method <p>quality of life (KVL-H), level of daily activities (KATz-ADL), physical<br /><br>functioning (Short Physical Performance Battery), metabolic equivalents level<br /><br>(Specific Activity Scale), self perceived effect. Possible associations with<br /><br>performance on exercise testing: for sarcopenia: fat-free mass (Bio Impedance<br /><br>Assessment and CT-scan), grip strength (JAMAR), risk of malnutrition (SNAQ);<br /><br>for cardiac anxiety: CAQ-DV, rate of perceived exertion (BORG-RPE); for<br /><br>comorbidity (Charlson comorbidity index); and for frailty (Edmonton frailty<br /><br>scale). </p><br>