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Clinical Trials/JPRN-jRCT1030220350
JPRN-jRCT1030220350
Recruiting
Phase 3

JCOG1915: Less intensive post-operative surveillance in low risk colorectal cancer patients - LESS study

Kanemitsu Yukihide0 sites680 target enrollmentSeptember 27, 2022

Overview

Phase
Phase 3
Intervention
Not specified
Conditions
Not specified
Sponsor
Kanemitsu Yukihide
Enrollment
680
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
September 27, 2022
End Date
TBD
Last Updated
2 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
Kanemitsu Yukihide

Eligibility Criteria

Inclusion Criteria

  • 1\) Pathologically proven colorectal adenocarcinoma.
  • 2\) Tumor is mainly located between cecum and lower rectum.
  • 3\) Tumor resection with D2 or D3 lymph node dissection with open or laparoscopic approach was performed, regardless of with or without lateral lymph node dissection (Robotic surgery is allowed for enrollment).
  • 4\) R0 resection was performed.
  • 5\) No distant metastasis defined as
  • 1\. Chest ; Chest CT or FDG\-PET/CT
  • 2\. Abdomen ; Abdomen CT or FDG\-PET/CT
  • 6\) 56 days after surgery.
  • 7\) pStage I cancer, or pStage II cancer without any following factors (JSCCR classification 9th ed.);
  • (a) Depth of tumor: pT4,

Exclusion Criteria

  • 1\) Synchronous or metachronous (within 5 years) malignancies
  • 2\) Infections which needs systemic treatment.
  • 3\) Severe psychological disease.
  • 4\) Continuous systemic corticosteroid or immunosuppressant treatment.
  • 5\) Routine thoracoabdominal and pelvic CT scan at least once a year due to past medical history / comorbidities.

Outcomes

Primary Outcomes

Not specified

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