Randomised evaluation of stents to open restricted airways in patients with centrally placed non-small cell lung cancer

Phase 3

Completed

• Conditions: Disease: Lung (non-small cell); Lung cancer; Subtopic: Lung Cancer; Topic: National Cancer Research Network; Cancer

• Registration Number: ISRCTN66557660
• Lead Sponsor: The Royal Marsden Hospital NHS Foundation Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2010-03-01
• Study Start: 2010-10-21
• Last Update Posted: 7 November 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 21

Inclusion Criteria

1. Able to give informed written consent in the English language
2. Male or female, aged greater than 18 years
3. Able and willing to attend St George's Hospital/Royal Marsden Hospital (RMH) for stent insertion (if allocated) and documentation of 6-minute walk distance (6MWD)
4. Willing to re-attend for follow-up and 6MWD at St George's Hospital/RMH 2 weeks later (all patients)
5. Diagnosis of non-small cell lung cancer (NSCLC) with centrally placed tumour with some degree of airway obstruction from information from bronchoscopy or computed tomography (CT) scan
6. Eastern Cooperative Oncology Group (ECOG) performance status 0 - 3

Exclusion Criteria

1. Relative contraindications to stenting, e.g. bleeding abnormality or relative anticoagulation problems
2. Pregnancy
3. Surgically resectable disease

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improvement in dyspnoea, measured at 2 weeks

Secondary Outcome Measures

Name	Time	Method
o secondary outcome measures.