Total Thyroidectomy Versus Hemithyroidectomy for Patients With Single Thyroid Nodule , Prospective Comparative Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 40
- 主要终点
- Improvement in the management of single thyroid nodule to reduce the morbidity and mortality rates
研究概览
简要总结
Thyroid nodules are common clinical problem. The incidence is 2-4 per 100,000 people per year, being more common in women and the elderly. thyroid nodule is a "discrete lesion within the thyroid gland that is radiologically distinct from the surrounding thyroid parenchyma. Most thyroid nodules are asymptomatic, may present as neck swelling
详细描述
Thyroid nodular disease comprises of a wide range of disorders. Benign forms such as colloid nodules,cysts and thyroiditis are more comman than benign follicular neoplasms and thyroid carcinomas. Incidence of malignancy ranges from 10% to 30% in solitary thyroid nodule(STN).Studies have shown that the occurrence of malignancy is higher in case of solitary thyroid nodule compared to multinodular goitres. Preoperative evaluation of thyroid nodules is important in distinguishing between benign and malignant thyroid nodules and also in treatment to avoid unnecessary extensive surgery and its complications. Fine needle aspiration biopsy (FNAB) is the most common method of examining solitary thyroid nodules today.Total thyroidectomy and lobectomy remain the main primary surgical interventions for single thyroid nodule. There is debat between total thyroidectomy and hemithyroidectomy for patients with single thyroid nodule. our study is for comparing between total thyroidectomy and hemi thyroidectomy in single thyroid nodule
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age from 20 to 60 years.
- •patients with single thyroid lesion
- •Fit for surgery
排除标准
- •patients with age less than 20 years and more than 60 years.
- •patients with multiple thyroid lesions.
- •patients with advanced and metastatic malignancy.
- •Unfit for surgery
研究组 & 干预措施
Total thyroidectomy for single thyroid nodule
group of participants will be treated with total thyroidectomy
干预措施: thyroidectomy (Procedure)
Hemithyroidectomy for single thyroid nodule
2nd group of participants will be treated with hemithyroidectomy
干预措施: thyroidectomy (Procedure)
结局指标
主要结局
Improvement in the management of single thyroid nodule to reduce the morbidity and mortality rates
时间窗: one year
Compare between total thyroidectomy and hemithyroidectomy in patients with single thyroid nodule to improve the management of single thyroid nodule in general surgery department , Assiut university hospital.
次要结局
未报告次要终点
研究者
Omar Anter Ali Abdelhamid
Principal Investigator
Assiut University