Emotion Recognition and Social Cognition in JME patients

• Conditions: Juvenile myoclonic epilepsy (JME); G40; Epilepsy

• Registration Number: DRKS00011216
• Lead Sponsor: niversitätsklinik für Neurologie der Paracelsus medizinischen Privatuniversität Salzburg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2016-10-21
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Inclusion criteria for patients:
- Electro-clinical diagnosis of JME based on Classification of the International League against Epilepsy
- Patients aged 14 years or older with willingness to participate in the project (informed consent will be obtained from all patients and/or parents of paediatric patients aged between 14 and 18 years)
- Patients with ability to participate in MRI and fMRI studies

Inclusion criteria for controls (healthy subjects and siblings of patients with JME):
- Healthy subjects and siblings of patients with JME aged 18 years or older with willingness to participate in the study

Exclusion Criteria

Exclusion criteria for patients:
- Occurrence of epileptic seizure <72 hours prior to MRI &fMRI study
- Patients with medical and/ or neurological illnesses other than JME (except for cluster B psychiatric disorders)
- Intake of Topiramate and / or Benzodiazepine
- Structural lesion on MRI
- Incompatibility with MRI investigation
- Pregnancy

Exclusion criteria controls (healthy subjects and siblings of patients with JME)::
- Individuals with medical and/ or neurological illnesses
- Individuals with EEG abnormalities (applies to siblings of patients with JME. All of them will undergo routine EEG)
- Structural lesion on MRI
- Incompatibility with MRI investigation
- Pregnancy

Study & Design

• Study Type: observational
• Study Design: Not specified