Emotion Recognition and Social Cognition in JME patients

niversitätsklinik für Neurologie der Paracelsus medizinischen Privatuniversität Salzburg0 sites200 target enrollmentOctober 21, 2016

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Juvenile myoclonic epilepsy (JME)
Sponsor: niversitätsklinik für Neurologie der Paracelsus medizinischen Privatuniversität Salzburg
Enrollment: 200
Status: Not yet recruiting
Last Updated: last year

No summary available.

Registry

who.int

Start Date

October 21, 2016

End Date

TBD

Last Updated

last year

Study Type

Observational

Sex

All

Sponsor

niversitätsklinik für Neurologie der Paracelsus medizinischen Privatuniversität Salzburg

•Inclusion criteria for patients:
•\- Electro\-clinical diagnosis of JME based on Classification of the International League against Epilepsy
•\- Patients aged 14 years or older with willingness to participate in the project (informed consent will be obtained from all patients and/or parents of paediatric patients aged between 14 and 18 years)
•\- Patients with ability to participate in MRI and fMRI studies
•Inclusion criteria for controls (healthy subjects and siblings of patients with JME):
•\- Healthy subjects and siblings of patients with JME aged 18 years or older with willingness to participate in the study

•Exclusion criteria for patients:
•\- Occurrence of epileptic seizure \<72 hours prior to MRI \&fMRI study
•\- Patients with medical and/ or neurological illnesses other than JME (except for cluster B psychiatric disorders)
•\- Intake of Topiramate and / or Benzodiazepine
•\- Structural lesion on MRI
•\- Incompatibility with MRI investigation
•\- Pregnancy
•Exclusion criteria controls (healthy subjects and siblings of patients with JME)::
•\- Individuals with medical and/ or neurological illnesses
•\- Individuals with EEG abnormalities (applies to siblings of patients with JME. All of them will undergo routine EEG)