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Clinical Trials/IRCT20200908048665N1
IRCT20200908048665N1CompletedPhase 2

Effects of extract of Foeniculum vulgare on serum levels of estrogen, progesterone, LH and FSH hormones and miR-499, BMP15 and GDF9 genes expression in granulosa cells of patients with polycystic ovary syndrome (PCOS)

Sanandaj University of Medical Sciences0 sites45 target enrollmentStarted: TBDLast updated:
Conditions

Trial Snapshot

Phase
Phase 2
Status
Completed
Sponsor
Enrollment
45

Study Overview

Brief Summary

No summary available.

Study Design

Study Type
Interventional

Eligibility Criteria

Ages
20 years to 35 years (—)
Sex
Female

Inclusion Criteria

  • According to the Adams criteria based on ovarian ultrasound manifestations is to have at least 10 cysts with a diameter of 2-8 mm around the central stroma, densely and in the form of a necklace.
  • Having Rotterdam diagnosis criteria (menstrual cycle disorder, clinical symptoms, and diagnosis of polycystic ovary in ultrasound diagnosed by a radiology specialist and infertility fellowship).
  • BMI between 18-22
  • Age between 20-35 years

Exclusion Criteria

  • Patients with Cushing's syndrome and weight-induced amenorrhea
  • Pituitary disorders
  • Congenital Adrenal Hyperplasia (CAH)
  • Prolactinoma
  • Thyroid disorders
  • Androgen-secreting tumors
  • Hypertension
  • Chronic kidney disease
  • Alcoholics and smokers
  • Previous miscarriage
  • Infertility in their husbands

Investigators

Sponsor
Sanandaj University of Medical Sciences

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