IRCT20200908048665N1CompletedPhase 2
Effects of extract of Foeniculum vulgare on serum levels of estrogen, progesterone, LH and FSH hormones and miR-499, BMP15 and GDF9 genes expression in granulosa cells of patients with polycystic ovary syndrome (PCOS)
Sanandaj University of Medical Sciences0 sites45 target enrollmentStarted: TBDLast updated:
Conditions
Trial Snapshot
- Phase
- Phase 2
- Status
- Completed
- Sponsor
- Enrollment
- 45
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 20 years to 35 years (—)
- Sex
- Female
Inclusion Criteria
- •According to the Adams criteria based on ovarian ultrasound manifestations is to have at least 10 cysts with a diameter of 2-8 mm around the central stroma, densely and in the form of a necklace.
- •Having Rotterdam diagnosis criteria (menstrual cycle disorder, clinical symptoms, and diagnosis of polycystic ovary in ultrasound diagnosed by a radiology specialist and infertility fellowship).
- •BMI between 18-22
- •Age between 20-35 years
Exclusion Criteria
- •Patients with Cushing's syndrome and weight-induced amenorrhea
- •Pituitary disorders
- •Congenital Adrenal Hyperplasia (CAH)
- •Prolactinoma
- •Thyroid disorders
- •Androgen-secreting tumors
- •Hypertension
- •Chronic kidney disease
- •Alcoholics and smokers
- •Previous miscarriage
- •Infertility in their husbands
Investigators
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