NL-OMON30478招募中3 期
A randomized, multicenter study to assess the efficacy on disease activity on enteric-coated mycophenolate sodium (EC-MPS, myfortic) versus continuation of azathioprine in patients with systemic lupus erythematosus on azathioprine maintenance therapy. - Myfortic versus azathioprine in SLE
适应症
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 48
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Systemic lupus on azathioprine
- •SLEDAI score equal or higher than 6
排除标准
- •1. Creatinine clearance of < 20ml/min
- •2. Patients with any clinically significant infection
- •3. Patients with known hypersensitivity to myfortic ® or to drugs with similar chemical structures
- •4. Patients with a history of malignancy of any organ system, treated or untreated, within the past 5 years whether or not there is evidence of local recurrence or metastases, with the exception of localized basal cell carcinoma of the skin
- •5. Patients with SLE active CNS manifestations or a past history of SLE CNS complications (e.g. psychosis, grand mal seizures)
- •6. Patients who have received prior therapy with mycophenolic acids (MPAs) (e.g. MMF)
- •7. Patients who have received an investigational drug within four weeks prior to study entry
- •8. females of childbearing potential who are planning to become pregnant, who are pregnant and/or lactating, who are unwilling to use effective means of contraception
研究者
相似试验
进行中（未招募）
1 期
A randomized, multi-center study to assess the effect of Darbepoetin alfa (Aranesp®) for the treatment of anemia in patients with advanced hormone independent prostate cancer and anaemia - DANCAPepoIn an open randomised, multi-center study to identify the haematopoietic response to Aranesp® (Darbepoetin 6,75 mcg/kg) administrated every fourth week compared to standard care of treatment in patients with anaemia due to hormone refractory prostate cancer with progression of skeletal metastases. A haematopoietic response is defined as haemoglobin concentration > 12 g/dl or increase in haemoglobin > 2 g/dl during the treatment phase.MedDRA version: 6.1Level: PTClassification code 10038444EUCTR2005-005658-37-DKDpt. of Urology -K. Aarhus University Hospital140
已完成
不适用
A multicenter randomized study evaluating the efficacy and safety of HMG-CoA reductase inhibitors (statins) in dyslipidemic patients with nephrosclerosis.ephrosclerosisJPRN-UMIN000007130Omihachiman Community Medical Center77
进行中（未招募）
不适用
A randomized, multicenter study, evaluating efficacy, safety, tolerability and pharmacokinetics of AEB071 combined with tacrolimus or mycophenolate mofetil (MMF) vs a tacrolimus-based control regimen in de novo liver transplant recipients - NDde novo liver transplant recipientsMedDRA version: 9.1Level: LLTClassification code 10024714Term: Liver transplantEUCTR2007-001776-36-ITOVARTIS FARMA320
进行中（未招募）
1 期
Trial to evaluate the efficacy of fentanyl pectin nasal spray (FPNS) versus Physician Choice (PC) - Usual Care (UC), in patients with head and neck cancer undergoing radiotherapy.Patients with head and neck cancer .MedDRA version: 21.1Level: PTClassification code 10067821Term: Head and neck cancerSystem Organ Class: 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)EUCTR2015-005110-30-ITFONDAZIONE IRCCS ISTITUTO NAZIONALE DEI TUMORI158
进行中（未招募）
1 期
A multicenter randomized trial to evaluate the efficacy of tocilizumab in patients with severe Coronavirus Disease 2019 (Covid-19) pneumonia failing glucocorticoids.polmonite severa da coronavirus 2019MedDRA version: 23.0Level: LLTClassification code 10053983Term: Corona virus infectionSystem Organ Class: 100000004862EUCTR2020-005291-35-ITAOU POLICLINICO DI MODENA640