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A study on the use of a subcutaneous injection to reduce skin side effects of breast brachytherapy with palladium seeds.

Conditions
breast cancer, brachytherapy, skin toxicity, spacer<br />mammacarcinoom, brachytherapie, huidtoxiciteit, spacer
Registration Number
NL-OMON23164
Lead Sponsor
Franciscus Gasthuis en Vlietland<br>Erasmus MC- Kanker Instituut
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
231
Inclusion Criteria

•Female

•Age 50 years or above

Exclusion Criteria

•Lymphovascular invasion

•Known allergy for hyaluronic acid

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Occurrence of teleangiectasia, following Bentzen's four point scale (LENTSOMA), after 2 years.
Secondary Outcome Measures
NameTimeMethod
local recurrence, disease free and overall survival,<br /><br>induration<br /><br>wound infection<br /><br>cosmetic results and health related quality of life<br /><br>costeffectiveness.<br /><br>Validation of a Dutch translation of the BCTOS questionnaire
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