Integrative Chinese and Western Medicine for Knee Osteoarthritis: Model of Patient Centered Healthcare and Shared Decision-making
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 228
- 主要终点
- WOMAC
研究概览
简要总结
This study aims to investigate if an integrated approach combining Traditional Chinese and Western medicine can better treat knee osteoarthritis. The goal is to see if this combined therapy can more effectively reduce pain severity and frequency, leading to an improved quality of life for KOA patients. Additionally, the study will explore the underlying mechanisms of pain and anti-inflammation related to KOA.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Factorial
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Male or female aged above 18 years old
- •Kellgren-lawrence grading scale ≥ II
- •Numerical rating scale (NRS) ≥ 4
排除标准
- •History of bone tumor
- •Pregnancy
- •History of bilateral knee replacement
- •Active infection
研究组 & 干预措施
Western medicine
Western medicine treatment only
干预措施: Western Medicine (Drug)
Herbal medicine and acupuncture
Western medicine combined herbal medicine and acupuncture
干预措施: herbal medicine and acupuncture (Procedure)
herbal medicine
Western medicine combined herbal medicine
干预措施: herbal medicine (Drug)
Acupuncture
western medicine combined acupuncture
干预措施: acupuncture (Procedure)
结局指标
主要结局
WOMAC
时间窗: From enrollment to 3 months after treatment completion.
Western Ontario and McMaster Universities Osteoarthritis (WOMAC) subscale
NRS
时间窗: From enrollment to 3 months after treatment completion.
Numerical rating scale (NRS) score for pain
Lequesne's index
时间窗: From enrollment to 3 months after treatment completion.
Lequesne's index
次要结局
未报告次要终点