Integrative Chinese and Western Medicine for Knee Osteoarthritis
- Conditions
- Knee Osteoarthristis
- Interventions
- Drug: Western MedicineProcedure: herbal medicine and acupunctureDrug: herbal medicineProcedure: acupuncture
- Registration Number
- NCT07072442
- Lead Sponsor
- Chang Gung Memorial Hospital
- Brief Summary
This study aims to investigate if an integrated approach combining Traditional Chinese and Western medicine can better treat knee osteoarthritis. The goal is to see if this combined therapy can more effectively reduce pain severity and frequency, leading to an improved quality of life for KOA patients. Additionally, the study will explore the underlying mechanisms of pain and anti-inflammation related to KOA.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 228
- Male or female aged above 18 years old
- Kellgren-lawrence grading scale ≥ II
- Numerical rating scale (NRS) ≥ 4
- History of bone tumor
- Pregnancy
- History of bilateral knee replacement
- Active infection
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- FACTORIAL
- Arm && Interventions
Group Intervention Description Western medicine Western Medicine Western medicine treatment only Herbal medicine and acupuncture herbal medicine and acupuncture Western medicine combined herbal medicine and acupuncture herbal medicine herbal medicine Western medicine combined herbal medicine Acupuncture acupuncture western medicine combined acupuncture
- Primary Outcome Measures
Name Time Method WOMAC From enrollment to 3 months after treatment completion. Western Ontario and McMaster Universities Osteoarthritis (WOMAC) subscale
NRS From enrollment to 3 months after treatment completion. Numerical rating scale (NRS) score for pain
Lequesne's index From enrollment to 3 months after treatment completion. Lequesne's index
- Secondary Outcome Measures
Name Time Method
Related Research Topics
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