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Clinical Trials/NCT02513732
NCT02513732
Completed
Not Applicable

XIENCE Xpedition Everolimus-Eluting Coronary Stent Japan Post Marketing Surveillance

Abbott Medical Devices11 sites in 1 country100 target enrollmentJuly 2014

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Ischemic Heart Disease
Sponsor
Abbott Medical Devices
Enrollment
100
Locations
11
Primary Endpoint
Number of Participants With Stent Thrombosis: Late
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

The objective of the study is to evaluate the safety and efficacy of XIENCE Xpedition Everolimus-Eluting 2.25mm Stent in real world practice in Japanese hospitals.

Detailed Description

Based on Good Post-marketing Study Practice (GPSP) regulation, general patient population with ischemic heart disease who are eligible for treatment with XIENCE Xpedition Everolimus-Eluting 2.25mm Stent will be registered, with no particular inclusion/exclusion criteria, and may be eligible for angiographic follow-up at eight months and clinical follow-up at one year. The XIENCE Xpedition 2.25 mm stent is composed of the stent identical to the stent of the XIENCE PRIME SV Stent.Therefore, the data collected from the PMS will be pooled with data collected from the ongoing XIENCE PRIME SV PMS for analysis.

Registry
clinicaltrials.gov
Start Date
July 2014
End Date
September 2020
Last Updated
4 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Number of Participants With Stent Thrombosis: Late

Time Frame: 30 days to 1 year post stent implantation-Day 212

Scaffold/Stent thrombosis should be reported as a cumulative value at the different time points and with the different separate time points. Time 0 is defined as the time point after the guiding catheter has been removed and the subject left the catheterization lab. Timings: Acute scaffold/stent thrombosis : 0 - 24 hours post stent implantation Subacute scaffold/stent thrombosis: \>24 hours - 30 days post stent implantation Late scaffold/stent thrombosis: 30 days - 1 year post stent implantation Very late scaffold/stent thrombosis: \>1 year post stent implantation

Secondary Outcomes

  • Number of Participants With Cardiac Death/All MI(0 to 5 years)
  • Number of Participants With Cardiac Death or Target-Vessel MI(0 to 5 years)
  • Mean Net Gain: In-stent, In-segment(At 8 months, post index procedure)
  • Mean Reference Vessel Diameter (RVD)(During follow-up, at 8 months post procedure)
  • Number of Participants With All Revascularization(0 to 5 years)
  • Number of Participants With Death(0 to 5 years)
  • Number of Participants With Target Lesion Revascularization Based on Ischemia Findings(0 to 5 years)
  • Number of Participants With Cardiac Death(0 to 5 years)
  • Number of Participants With MI Related to Target Vessel(0 to 5 years)
  • Number of Participants With Target Vessel Failure (TVF)(0 to 5 years)
  • Number of Participants With Target Vessel Revascularization (Non-TLR)(0 to 5 years)
  • Percent Diameter Stenosis (%DS)(During follow-up, at 8 months post procedure)
  • Number of Participants Using Antiplatelet Therapy(5 years observation day from the procedure day)
  • Number of Participants With Myocardial Infarction(0 to 5 years)
  • Number of Participants With Death,Myocardial Infarction and Revascularization (DMR)(0 to 5 years)
  • Number of Participants With Target Vessel Revascularization (TLR or TVR (Non-TLR))(0 to 5 years)
  • Number of Participants With Cardiac Death/All MI/ID-TLR (Major Adverse Cardiac Events-MACE)(0 to 5 years)
  • Number of Participants With Target Lesion Failure (TLF)(0 to 5 years)
  • Mean Lesion Length(Pre-procedure)
  • Number of Participants With Death/All MI(0 to 5 years)
  • Mean Acute Gain: In-stent, In-segment(At 8 months, post index procedure)
  • Mean Late Loss(LL): In-stent, In-segment, Proximal, and Distal(At 8 months, post index procedure)
  • Minimum Blood Vessel Diameter(During follow-up, at 8 months post procedure)

Study Sites (11)

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