The effect of rosuvastatin in multiple sclerosis
- Conditions
- Multiple sclerosis.Multiple sclerosis
- Registration Number
- IRCT20210211050323N1
- Lead Sponsor
- Hamedan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
History of multiple sclerosis at least one year ago
Radiographic findings of magnetic resonance imaging ( MRI ) consistent with the clinical diagnosis of multiple sclerosis
No other concomitant inflammatory disease
Bad cholesterol levels (low-density lipoprotein) less than 130 mg / dL
No pregnancy and lactation
The consistency of the main treatment of patients and the use of a specific type of drug
Do not take medications other than standard treatments for multiple sclerosis that alter the levels of the factors under consideration.
Do not use any combination with antioxidant effects in the past month.
Existing evidence based on increased patient disability
Consumption of any combination or drug with antioxidant effects except prescription drugs
Existence of any cognitive or behavioral disorders that lead to the patient not cooperating.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum Catalase Levels. Timepoint: Before the intervention and 3 months after the start of the intervention. Method of measurement: Spectrophotometry.;Serum levels of superoxide dismutase. Timepoint: Before the intervention and 3 months after the start of the intervention. Method of measurement: Spectrophotometry.;Serum thiol level. Timepoint: Before the intervention and 3 months after the start of the intervention. Method of measurement: Spectrophotometry.
- Secondary Outcome Measures
Name Time Method Expanded Disability Status Scale (EDSS ) score. Timepoint: Before the intervention and 3 months after the start of the intervention. Method of measurement: Expanded Disability Status Scale (EDSS) questionnaire.