Comparative Study of Gingival Depigmentation Using Injectable Glutathione, Vitamin C and Tranexamic Acid with and without Low-Level Laser Therapy: Randomized Controlled Clinical Trial
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
研究概览
简要总结
This is a comparative evaluation of injectable glutathione, vitamin C and tranexamic acid in gingival depigmentation with and without low level laser therapy- a randomized controlled clinical trial. parameters evaluated are dummet gupta oral pigmentation index, plaque ad gingival index, healing index. vitamin C is a potent antioxidant, tranexamic acid inhibits plasmin activity , glutathione converts eumelanin to pheomelanin and low level laser theray aids in healing , fibroblast proliferation and prevetns inflammation. however there is paucity of literature comparing the use of injectable lutathione, vitamin C and tranexamic acid with and without low level laser therpay in gingival depigmenation. therefore, our study aims at comparing the use of injectable glutahione, vitamin C and tranexamic acid with and without low level laser therapy in gingival depigmentation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- All
入选标准
- •Systemically healthy patients 2) Presence of gingival hyperpigmentation in maxillary and/ or mandibular sextants 3) Age 18–40 years 4) High esthetic concern.
排除标准
- •Smokers 2) Pregnant or lactating women 3) Patients with systemic diseases affecting pigmentation 4) History of previous depigmentation treatment.
研究者
DR MANALI SHASHIKANT WAGHMARE
VYWS dental college and hospital