Prospective observational study to evaluate using OCT in stent neoatherosclerosis for patients after Everolimus-eluting stent (EES) implantation in the late phase.
Not Applicable
Recruiting
- Conditions
- coronary artery disease
- Registration Number
- JPRN-UMIN000033927
- Lead Sponsor
- Kobe University Graduate School of Medicine, Division of Cardiovascular Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
Not provided
Exclusion Criteria
1)Patients who can not written consent 2)Patient judged inappropriate by the attending physician
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method It is aim to evaluate the presence of neoatherosclerosis using OCT in late phase of Everolimus eluting stent implantation, and to examine related factors.
- Secondary Outcome Measures
Name Time Method 1)Various data obtained by OCT (Minimum lumen area, Minimum stent area, Average neointimal thickness, Lipid arc, Lipid length, Lipid index, Neoatherosclerosis, Thin cap fibroatheroma(TCFA), Macrophage grade, Peri-strut low intensity areas(PLIA), Neointimal rapture, Thrombi, Neointimal calcification 2)laboratory data (Total cholesterol, LDL-cholesterol, HDL-cholesterol, Triglyceride, small LDL-C, ApoA-1, ApoB, ApoB/ApoA-1 ratio, Lp(a), TNF-a, IL-6, MMP-9, Fasting plasma glucose, HbA1c 3)Safety endpoint; Major cardiovascular events (MACE), All cause death, Non-cardiac death