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临床试验/ISRCTN81718275
ISRCTN81718275已完成未知

A randomised controlled trial to examine the effects of calcimimetic therapy on bone and cardiovascular health in end-stage renal disease

Salford Royal NHS Foundation Trust (UK)0 个研究点目标入组 40 人开始时间: 2008年7月31日最近更新:

试验速览

阶段
未知
状态
已完成
发起方
入组人数
40

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

性别
All

入选标准

  • 1. Age 18-75 at recruitment, both male and female
  • 2. On haemodialysis for >90 days
  • 3. Parathyroid hormone (PTH) >=300 pg/ml
  • 4. Corrected calcium >=2.1 mmol/l

排除标准

  • 1. Atrial fibrillation
  • 2. Any contra-indications to magnetic resonance (MR) scan or ability to cooperate with scan
  • 3. Any factors which will influence computed tomography (CT) scan e.g. artificial heart valves, previous sternotomy wires, stents
  • 4. Contra-indication to cinacalcet e.g., pregnant, breast feeding, known reaction
  • 5. Moderate to severe liver disease (alanine transaminase [ALT] >3x normal)
  • 6. Have a poor record of compliance with medication
  • 7. Have participated in a study involving an investigational drug during the 30 days prior to the first visit
  • 8. Be involved in any other research study which exposes the patient to radiation above that of normal clinical practice

研究者

发起方
Salford Royal NHS Foundation Trust (UK)

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