High Or low dose Syntocinon® for delay in labour
- Conditions
- ulliparous women with a singleton cephalic pregnancy at term (37-42 weeks gestation) with confirmed delay in labour and ruptured membranes as defined by NICE Intrapartum Care Guidelines for whom the clinical decision has been made to prescribe Syntocinon for augmentation of labour.Pregnancy and Childbirth
- Registration Number
- ISRCTN99841044
- Lead Sponsor
- Birmingham Womens NHS Foundation Trust
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 1500
1. Nulliparous women with singleton cephalic pregnancy at term (37-42 weeks gestation)
2. Confirmed delay in labour and ruptured membranes for whom the clinical decision has been made to prescribe Syntocinon for augmentation of labour
According to NICE guidance [NICE 2014], labour is established when there are regular painful contractions and progressive cervical dilation from 4 cm. Delay is suspected when cervical dilation of < 2 cm in 4 hours occurs once labour is established. Delay is confirmed when progress of <1 cm in 2 hours is found on repeat vaginal examination.
1. Multiparous women
2. Nulliparous women who:
2.1. Are undergoing induction of labour
2.2. Have a BMI >40 at booking
2.3. Have a multiple pregnancy
2.4. Have existing cardiac disease, bleeding disorders, diabetes (either pre-existing or gestational), previous uterine surgery
2.5. Have had significant antepartum haemorrhage
2.6. Are under 16 years of age
2.7. Have a known contra-indication to oxytocin therapy as listed in the Summary of marketing Product Characteristics
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of caesarean section, data taken from medical notes
- Secondary Outcome Measures
Name Time Method