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Yoga and Aerobic Exercise Effects on Cognition

Not Applicable
Completed
Conditions
Stress, Psychological
Interventions
Behavioral: Seated rest
Behavioral: Aerobic exercise
Behavioral: Sun salutations
Registration Number
NCT04077645
Lead Sponsor
University of Illinois at Urbana-Champaign
Brief Summary

The purpose of this acute randomized control study is to assess the feasibility of a low-to-moderate intensity Yoga intervention (i.e. sun salutations), and examine its effect on cognitive functioning, compared to engaging in aerobic activity or seated rest. Participants will include individuals who are currently experiencing symptoms of psychosocial stress or general anxiety.

Detailed Description

Eligible participants will be randomized to one of three groups: 1. Sun salutations (Yoga), 2. Aerobic exercise (walking on a treadmill), 3. Seated rest (watching educational videos). Each activity will be 30 minutes in duration. Immediately before and after the 30 minute intervention, participants will undergo psychosocial and cognitive assessments. Prior to the intervention, participant's physical activity will be tracked for one week, via a consumer grade accelerometer.

Baseline and post-intervention testing will include a cognitive battery, psychosocial questionnaires, flexibility testing and physiological measures.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
71
Inclusion Criteria
  • Anyone between the ages of 18-45 years

  • Anyone with a score of 3 or higher on the Generalized Anxiety Disorder symptom checklist of the Diagnostic and Statistical Manual 5. That is, anyone meeting 3 or more symptoms, on more days of the week than not, for the past 6 months:

    1. Restlessness, feeling keyed up or on edge. 2. Being easily fatigued. 3. Difficulty concentrating or mind going blank. 4. Irritability. 5. Muscle tension. 6. Sleep disturbance (difficulty falling or staying asleep, or restless, unsatisfying sleep).
  • Ability to exercise at moderate to vigorous activity levels (defined as 50%-75% of the adjusted age-predicted maximum heart rate)

  • Access to a smartphone and willingness to allow research staff to install a mobile activity tracker application (and space to allow for installation)

  • Willingness to be randomized into one of three groups

Exclusion Criteria
  • Anyone who is physically active (≥30 minutes, 2 or more times/week, for the last 3 months) and/or a regular practitioner of Yoga or mind-body activities (≥30 minutes, 2 or more times/week, for the last 3 months).
  • Anyone with serious chronic medical conditions that would preclude them from participating without a physician present, or anyone with a risk of seizure, or anyone having psychiatric and/or neurological disorders.
  • Anyone who does not consent to wearing the Fitbit, or does not have a smartphone that allows us to download an app on their phone.
  • Pregnant women.
  • Anyone incapable of performing the following movements at a moderate intensity- sitting, standing, kicking, pulling, pushing, bending one's elbows, bending the body forward, bending one's knees, lying down and getting up.
  • Anyone with blood pressure of 200/105 or more, and anyone who scores 1 or more on the Physical Activity Readiness Questionnaire
  • Anyone refusing or unwilling to be randomized into either of the conditions.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Seated rest (attentional control)Seated restWatching educational videos for 30 minutes.
Aerobic exerciseAerobic exerciseWalking on a treadmill at low to moderate intensity for 30 minutes.
Sun salutationsSun salutationsSun salutations, breathing exercises, and relaxation, at a low to moderate intensity, for 30 minutes.
Primary Outcome Measures
NameTimeMethod
n-back task (Working memory)Change from baseline performance on the n-back at 30 minutes

This is a computerized task measuring the working memory domain of cognition. The task had 3 conditions, namely, 0-back, 1-back and 2-back. Participants are presented with a series of stimuli one after the other. They have to decide whether the stimulus currently presented is the same as the stimulus presented "n" items before. For the 1-back task, participants have to decide whether the stimulus matches the stimulus presented 1 earlier. For the 2- back task, they have to decide whether the stimulus matches the stimulus presented 2 earlier. Reaction time and accuracy of the response are recorded.

Secondary Outcome Measures
NameTimeMethod
Visual Analog Scale for stressChange from baseline performance at 30 minutes

Participants have to indicate how stressed they are currently feeling on a scale ranging from 0 (none) to 100 (as bad as it gets). Higher scores mean more stress.

Feeling ScaleChange from baseline performance at 30 minutes

This scale measures how a participant is feeling at the present moment (valence) after a bout of exercise. It is an 11-point one-item measure ranging from +5 (very good) to -5 (very bad). Higher scores represent positive affect.

Heart RateChange from baseline performance at 30 minutes

Participants' heart rate will be measured using an oxymeter

Rating of Perceived ExertionDay 1

Participants are asked to self rate their feeling of exertion on a 11 point scale, ranging from 6 (no exertion) to 20 (maximal exertion), for the activity they were engaged in during the intervention.

Rating of Enjoyment and InterventionDay 1

Participants will rate their enjoyment in terms of the delivery method and the intervention. This will include questions such as 'Did you like the video instruction for sun salutations?', 'Would you recommend this activity to your family and friends?' This will also include a semi-structured interview with those in the sun salutation group. For example, 'What about this activity did you find challenging?', 'To what extent did you enjoy the sun salutations activity?'

Trail Making test A and B (Global cognition)Change from baseline performance at 30 minutes

This is a paper pencil task having 2 parts- Trails A and Trails B, with Trails B being more complex. In Trails A, there are 25 circles on a piece of paper numbered 1-25. Participants have to join these numbers in ascending order, as quickly as they can, without lifting their pencil. In Trails B, the participants have to join 25 circles in an ascending order, but they have to alternate between numbers and letters (1-A-2-B-3-C). Time to complete the task correctly is recorded.

State Trait Anxiety QuestionnaireChange from baseline performance at 30 minutes

This questionnaire has 20 items for assessing state anxiety. Participants respond on a 4-point scale ("Not at all" to "Very much so"). Higher scores indicate greater anxiety.

Focus of AttentionDay 1

Participants are asked to self rate (1 item) their focus of attention while engaged in the previous activity. Responses range from 0 (Internal thoughts) to 10 (external thoughts), with higher scores representing external focus of attention.

Digit Symbol Substitution Test (Processing Speed)Change from baseline performance at 30 minutes

In this task, participants are presented with a code key, in which numbers 1-9 are matched with a unique symbol. Then, they are presented with a sheet of paper having a series of symbols on it. Using the codekey, participants have to read aloud, the numbers that the symbols are associated with, in 2 minutes. The accuracy is recorded.

Perceived Mental FatigueChange from baseline performance at 30 minutes

Participants self rate their present moment feelings on a scale from 1 - 5 (1=not true at all, 5=very true) yielding a mean score across all 7 items, with higher scores indicating greater mental fatigue.

Rating of Technology Ease of Use and UsabilityDay 1

Participants will rate the technology used to deliver the intervention, in terms of its ease of use and usability. The items are based on the Technology Acceptance Model and will include questions such as 'The Yoga video was clear and understandable.'

Trial Locations

Locations (1)

University of Illinois at Urbana-Champaign

🇺🇸

Urbana, Illinois, United States

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