ISRCTN61064041
Completed
未知
Evaluation of non-invasive automatic measurement protocol for dry eye diagnosis in patients with dry eye disease and control subjects
uzerner Kantonsspital0 sites75 target enrollmentDecember 24, 2020
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Dry eye syndrome, dry eye disease
- Sponsor
- uzerner Kantonsspital
- Enrollment
- 75
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35543570/ (added 29/06/2022)
Investigators
Eligibility Criteria
Inclusion Criteria
- •All participants:
- •1\. Aged between 18 and 79 years
- •2\. Given consent and signed the consent form declaration
- •1\. Ocular Surface Disease Index (OSDI©) score \=13
- •2\. At least one of the following:
- •2\.1\. Image result for tear break\-up time (TBUT) of \=10 sec
- •2\.2\. Corneal staining grading \=grade II
- •2\.3\. Schirmer test \=10 mm in 5 min
- •Control subjects:
- •1\. OSDI© score \<13
Exclusion Criteria
- •1\. Eyelid deformities or eyelid motility disorders (such as incomplete lid closure, entropium, ectropium, hordeola, or chalazia)
- •2\. Previous ocular disease leaving sequelae or requiring current topical eye therapy
- •3\. Active ocular allergy
- •4\. Known hypersensitivity to sodium fluorescein or oxybuprocaine
- •5\. LASIK or PRK surgery performed
- •6\. Punctal plugs or cauterization within the past 30 days
- •7\. Abormality of nasolacrimal drainage
- •8\. Pregnancy or lactation
- •9\. Systemic disease known to affect tear production or loss, diagnosed or being instable within the past 30 days
- •10\. Started or changed dose of chronic systemic medication known to affect tear production within the past 30 days
Outcomes
Primary Outcomes
Not specified
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