The Effect of Positive Pressure and Body Position on Volumetric Capnography Assessed by Electrical Impedance Tomography
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- Analysis of the changes in volumetric capnographic parameters with changes in body positioning and positive pressure ventilation.
研究概览
简要总结
Volumetric capnography is an interesting and non-invasive tool for monitoring ventilation in mechanically ventilated patients. The aim of this study was to test the effect of positive pressure ventilation and different body positions on volumetric capnograms.
详细描述
In this interventional study awake and healthy volunteers will be submitted to spontaneous, pressure support and control pressure ventilation using a tight nasal mask. Volumetric capnography and electrical impedance tomography (EIT) will be continuously recorded during the protocol. Different body positions were randomly tested. Analysis of global and regional distribution of ventilation using EIT will be matched with changes observed in volumetric capnography-derived parameters.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 28 Years 至 39 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •American Society Anesthesia physical status I.
- •Age between 25-39 years old,
- •Body mass index between 23-28 kg/m2,
- •Non-smokers.
排除标准
- •Presence of pulmonary or cardiac diseases.
- •Abnormal spirometry.
研究组 & 干预措施
non-invasive ventilation
Non-invasive positive pressure at different body positions: sitting - supine - prone - right lateral and left lateral.
干预措施: body positions (Other)
结局指标
主要结局
Analysis of the changes in volumetric capnographic parameters with changes in body positioning and positive pressure ventilation.
时间窗: 4 hours
The volunteers are breathing spontaneously with and without positive pressure support. Capnographic parameters were registered at each studied condition.
次要结局
- Electrical impedance images of the distribution of ventilation with changes in body positioning and positive pressure ventilation.(4 hours)