Evaluating of Brain Activity through Transcranial Magnetic Stimulation on the Primary Auditory Cortex
Not Applicable
- Conditions
- Sensorineural hearing loss
- Registration Number
- JPRN-UMIN000051793
- Lead Sponsor
- Kyoto University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Not provided
Exclusion Criteria
Have difficulty understanding explanations or instructions due to cognitive impairments. Have a history of organic brain disorders or neurological diseases in the family. Have a pacemaker implanted. Already have a cochlear implant. Have non-ferromagnetic materials in the body that cannot be confirmed to be non-magnetic (such as aneurysm clips, mechanical heart valves, neural stimulation devices, insulin pumps, intraocular metals, etc.). If deemed unsuitable based on the "Transcranial Magnetic Stimulation (TMS) Examination Pre-checklist" and the "MRI Examination Pre-checklist." Any other individuals deemed inappropriate as research subjects by the principal investigator.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method atency and Amplitude of Transcranial Evoked Potential, and Time Frequency Analysis Power
- Secondary Outcome Measures
Name Time Method Amplitude and Time-Frequency Analysis Power of Resting-state and Auditory Stimulus Task-elicited Brain Waves, Latency of Evoked Brain Waves during Auditory Stimulus Task, and Changes in these Measures before and after Cochlear Implant Surgery. Correlation between Brain Wave Examination Results and Speech Discrimination Ability, Correlation between Cochlear Implant Thresholds and Speech Discrimination Ability at the Postoperative Six-month Mark, and Brain Wave Results. Functional Connectivity of Various Cortical Regions in Resting-state MRI and Changes in Connectivity before and after Cochlear Implant Surgery. Cognitive Function Evaluation (assessed with TMT, MMSE, and React Kyoto).