The evaluation of relationship between insulin resistance and mood disorders in patients with polycystic ovarian syndrome
Phase 2
- Conditions
- Polycystic ovary syndrome.Polycystic ovarian syndrome
- Registration Number
- IRCT201601106710N6
- Lead Sponsor
- Vice Chancellor for Research of Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 40
Inclusion Criteria
patients with PCOS who meet the Rotterdam criteria; with top 10 score in Anxiety Inventory and top 14 score in the Beck Depression Inventory.
Exclusion criteria: patient's consent to continue the study; patients who have been treated PCOS over recent 3 months; patients treated with anxiety disorders and depression; patients with diabetes; Patients with Cushing disease; hyperprolactinemia; congenital adrenal hyperplasia; Patients with serious illnesses and life threatening disease (including cancer, cirrhosis, renal failure; severe heart failure class 3 and 4 serious lung disease); pregnancy and lactation.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Anxiety and depression scores. Timepoint: Baseline and three months after treatment with metformin. Method of measurement: Based on questionnaire.
- Secondary Outcome Measures
Name Time Method Insulin resistance. Timepoint: Baseline and three months after treatment with metformin. Method of measurement: Test.