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临床试验/ISRCTN41671021
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Avoiding Late Diagnosis of Ovarian Cancer (ALDO)

niversity College London0 个研究点目标入组 875 人开始时间: 2020年2月17日最近更新:
适应症

试验速览

阶段
未知
状态
已完成
发起方
入组人数
875

研究概览

简要总结

2022 Results article in http://dx.doi.org/10.1136/jmg-2022-108741 (added 18/08/2023)

研究设计

研究类型
Interventional

入排标准

性别
Female

入选标准

  • 1. Women who have tested postive for a pathogenic BRCA1 or BRCA2 mutation
  • 2. Women aged 35 years or over
  • 3. Women who still have at least one ovary or fallopian tube in situ
  • 4. Women who are able and willing to travel to one of the named referral centres

排除标准

  • 1. Women who have tested negative for pathogenic BRCA1 or BRCA2 gene mutation
  • 2. Women who have not been tested for a pathogenic BRCA1 or BRCA2 gene mutation
  • 3. Women who are less than 35 years of age
  • 4. Women who are pregnant are not eligible for the ROCA® Test until 6 weeks after the end of their pregnancy. Neither CA125 nor ultrasound scanning can be used reliably to screen for OC during pregnancy
  • 5. Women with a past history of bilateral salpingo-oophorectomy (Note: Women who still have one or more fallopian tube or ovary in situ are still eligible as they remain at increased risk of ovarian/tubal cancer)
  • 6. Women previously treated for an ovarian malignancy
  • 7. Women who are under investigation for suspected OC
  • 8. Women currently being treated or within 6 weeks of treatment for any other malignancy

研究者

发起方
niversity College London

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