A study employing a serial reaction time task (SRT) in persons with autism

Conditions: F84.5
Asperger syndrome

Registration Number: DRKS00017167

Lead Sponsor: Klinik und Poliklinik für Psychiatrie und Psychotherapie der Uniklinik Köln

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 80

Inclusion Criteria

Healthy controls: Clinical and anamnestic exclusion of neurological and psychiatric diseases; no current psychotropic medication; age between 18 and 50 years; legally effective written consent of the volunteer to participate in the study (information sheet); normal visual acuity requiring no visual aids.

Selection of diagnosis group F84.5 (ASS): Membership of diagnosis group F84.5 (Asperger's syndrome) according to ICD-10; clinical and anamnestic exclusion of comorbid neurological and psychiatric diseases; age between 18 and 50 years; legally effective, written declaration of consent of the patient to participate in the study (information sheet); normal visual acuity not requiring visual aids.

Exclusion Criteria

Underage persons and persons older than 65 years; Current or previous diagnosis of a psychiatric or neurological disease; Presence of internal diseases (malignant tumor disease, HIV infection); Previously known MRI or EEG abnormalities; Acute suicidal tendencies, self endangering or conduct endangering others; Absence of legally effective declaration of consent, persons without legal capacity and persons in official or judicial custody (PsychKG, BTG); Visual acuity requiring visual aids.

Study & Design

Study Type: observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Implicit vs. explicit learning using a reproductive task in people with autism spectrum disorder.<br><br>The aim is to determine the severity of autistic symptoms in all participants with the help of the autism quotient (AQ) and the emotion quotient (EQ). With the help of the Wechsler Intelligenzscala für Erwachsene (WAIS-IV) the general cognitive performance is to be recorded. These general tasks should not take more than 100 minutes in total. <br><br>The actual duration of the SRT is max. 60 minutes (=1 hour) per person. <br><br>In total max. 160 minutes.

Secondary Outcome Measures