Prophylactic effects of ondansetrone
Phase 2
- Conditions
- Maxillofacial operations: trauma-orthognathic surgery.Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
- Registration Number
- IRCT201108147324N1
- Lead Sponsor
- Vice Chancellor for Research, Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 175
Inclusion Criteria
patients candidate for maxillofacial surgery; 18-50 years of age; Patients undergoing IMF.
Exclusion criteria: systemic diseases affecting nausea and vomiting; brain trauma in traumatic patients, as a factor influencing nausea and vomiting; clinical conditions indicating presence of factors for being placed in a high risk group; duration of surgery more than 3 hours; use of nausea- and vomiting-inducing drugs such as opiates.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ausea. Timepoint: On arrival at the ward (full consciousness),Thirty minutes after full consciousness,An hour after full consciousness Thirty minutes after PO (nearly 4.5 hours after full consciousness),Eight hours after full consciousness,. Twenty hours after surgery. Method of measurement: Recorded by inspection of nausea and asking after recovery.;Vomiting. Timepoint: On arrival at the ward (full consciousness),Thirty minutes after full consciousness,An hour after full consciousness Thirty minutes after PO (nearly 4.5 hours after full consciousness),Eight hours after full consciousness,. Twenty hours after surgery. Method of measurement: recorded by inspection of vomiting.
- Secondary Outcome Measures
Name Time Method Vertigo. Timepoint: On arrival at the ward (full consciousness),Thirty minutes after full consciousness,An hour after full consciousness Thirty minutes after PO (nearly 4.5 hours after full consciousness),Eight hours after full consciousness,. Twenty hours after surgery. Method of measurement: Inspection and asking from the patient.