EFECAB: Improving Pig Management to Prevent Epilepsy in Burkina Faso

Not Applicable

Completed

• Conditions: Cysticercosis
• Interventions: Other: Educational package

• Registration Number: NCT03095339
• Lead Sponsor: University of Oklahoma

Brief Summary

This is a pre-post randomized community-based controlled trial aimed at estimating the effectiveness of an educational package developed using PRECEDE PROCEED to reduce the cumulative incidence of Taenia solium cysticercosis in three Provinces of Burkina Faso. The study design included an 18-months baseline study to measure baseline cumulative incidence of cysticercosis followed by an 18-month post randomization study to measure the effectiveness of the intervention. Sixty villages of three Provinces of Burkina Faso were included. The primary outcome was the change in the baseline to post randomization cumulative incidence in the intervention group compared to the control group.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-02-21
• Primary Completion: 2014-11-24
• Study Completion: 2015-01-31
• Study First Submitted: 2017-03-22
• Study First Submitted QC: 2017-03-22
• Study First Posted: 2017-03-29
• Status Verified: 2018-03
• Last Update Submitted: 2018-03-30
• Last Update Posted: 2018-04-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 58

Inclusion Criteria

• Population of at least 1000 at the 2006 census
• Present on the map of the "Institut Géographique du Burkina 2000"
• Separated from another village by at least 5 kilometers.

Exclusion Criteria

• Village located on a National or Provincial road
• Village located within 20 km of Koudougou or Ouagadougou
• Regional or Provincial Capital
• Absence of pigs in the village

At the individual level, the following eligibility criteria were used:

Inclusion Criteria:

• Aged 5 years old or more
• Has lived in the village for at least 12 months
• Not planning to move in the next three years

Exclusion Criteria:

• Presence of confirmed epilepsy or progressively worsening severe chronic headaches at baseline.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Educational package	Educational package	The educational package included the offering of the Self-Esteem , Associative strengths, Resourcefulness, Action-planning and Responsibility (SARAR) Participatory Hygiene and Sanitation Transformation (PHAST) approach, a 52 minutes educational movie and accompanying cartoon booklet. The package was developed using the PRECEDE approach.

Primary Outcome Measures

Name	Time	Method
Human active cysticercosis cumulative incidence	baseline, 18 months follow-up pre randomization, 18 months follow-up post randomization	Sero conversion to the AgELISA test to detect antigens of cysticercosis

Secondary Outcome Measures

Name	Time	Method
Porcine active cysticercosis prevalence	baseline, 18 months follow-up pre randomization, 18 months follow-up post randomization	Sero-positivity to the AgELISA test to detect antigens of cysticercosis
Change in knowledge, attitude and practices	baseline, 18 months follow-up pre randomization, 18 months follow-up post randomization	Change in answers to the questionnaire through time
Stigmatization of epilepsy	18 months follow-up post randomization	Attitudes and knowledge regarding epilepsy post randomization
Cumulative incidence of epilepsy and progressively worsening severe chronic headaches	baseline, 18 months follow-up pre randomization, 18 months follow-up post randomization	development of neurological disorders among those followed up at least twice

Trial Locations

Locations (1)

AFRICSanté; 🇧🇫 Bobo Dioulasso, Burkina Faso