The utility of 11C-choline PET/CT in prostate patients of PSA failure

Not Applicable

Recruiting

• Conditions: Prostate Cancer

• Registration Number: JPRN-UMIN000019029
• Lead Sponsor: Radiology, Hyogo College of Medicine

Brief Summary

Twenty Japanese prostate cancer patients underwent 11C-choline and FDG PET/CT. The sensitivity/specificity/accuracy/AUC for choline-PET for diagnosing local lesions were 90.9%/100%/95.0%/1.0, whereas those for FDG-PET were 45.5%/100%/75.0%/0.773. Those for choline-PET for node metastasis were 88.9%/100%/95.0%/0.944, and those for FDG-PET were 44.4%/100%/75.0%/0.722. Those for choline-PET for bone metastasis were 84.6%/100%/90.0%/0.951, and those for FDG-PET were 76.9%/100%/85.0%/0.962.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-10-01
• Last Update Posted: 20 November 2023
• Study Completion: 2025-12-31

Recruitment & Eligibility

• Status: Recruiting
• Sex: Male
• Target Recruitment: 20

Inclusion Criteria

Not provided

Exclusion Criteria

*The patients who cannot keep face up position because of sharp pain in succession for around 30 minutes. *The patients with the extreme claustrophobia. *The patients whom the ADL which I become independent and can inspect is not kept. *The patients who a study person in charge is judged to be inappropriate.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare diagnostic accuracy (ROC analysis, sensitivity, specificity, and accuracy) for diagnosing lymph node recurrence between 11C-choline PET/CT and chest/abdomen CT.

Secondary Outcome Measures

Name	Time	Method
To compare diagnostic accuracy (ROC analysis, sensitivity, specificity, and accuracy) for diagnosing local recurrence and distant metastasis and clinical impact between 11C-choline PET/CT and chest/abdomen CT.