The Effect of Vocal Rest Versus Vocalization Following Xeomin® Injections in Spasmodic Dysphonia
Not Applicable
- Conditions
- Adductor Spasmodic Dysphonia
- Registration Number
- NCT03129087
- Lead Sponsor
- Lawson Health Research Institute
- Brief Summary
This study will compare the effects of vocal rest versus continuous vocalization for one hour immediately following botulinum toxin injections for adductor spasmodic dysphonia.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
- Diagnosed with adductor spasmodic dysphonia (ADSD) by an experienced neurologist and otolaryngologist. ADSD patients who have been stabilized on their treatment dose for at least 2 treatment cycles.
Exclusion Criteria
- Diagnosed with another neurological disorder that is combined with ADSD (i.e. Parkinson's disease and ADSD). Previous history of an additional vocal pathology (i.e. vocal polps, vocal nodules, unilateral vocal fold paralysis, etc.)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Severity of spasmodic dysphonia symptoms Six weeks post-treatment Acoustic measures and perceptual ratings of vocal spasm severity
Patient-reported outcome measures of symptoms and communication six weeks post-treatment Six patient-reported questionnaires related to symptoms, communication effectiveness, quality of life, and self-efficacy
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
LawsonHRI
🇨🇦London, Ontario, Canada
LawsonHRI🇨🇦London, Ontario, Canada