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Floatation-REST and Anorexia Nervosa

Not Applicable
Active, not recruiting
Conditions
Anorexia Nervosa
Interventions
Behavioral: Floatation-REST plus usual care
Behavioral: Usual care
Registration Number
NCT03610451
Lead Sponsor
Laureate Institute for Brain Research, Inc.
Brief Summary

The study proposed in this protocol aims to document the effect of Floatation-REST (reduced environmental stimulation therapy) on symptoms of anorexia nervosa.

Detailed Description

Flotation-REST (reduced environmental stimulation therapy) alters the balance of sensory input by systematically attenuating signals from the visual, auditory, thermal, tactile, vestibular, and proprioceptive systems. Previous research has shown that this heightens interoceptive awareness and reduces anxiety in clinically anxious populations. Anorexia nervosa (AN) is characterized by elevated anxiety, distorted body image, and disrupted interoception, raising the question of whether floatation therapy might positively impact these symptoms. A recent safety study found that Floatation-REST was well tolerated by individuals weight-restored outpatients with current or prior AN. Additionally, participants reported improvements in affective state and body image disturbance following floating, raising the possibility that this intervention might be investigated for clinical benefit in more acutely ill cases.

The primary aim of this study is to begin to examine the effect of Floatation-REST on body image disturbance in inpatients with AN. Secondary aims including determining whether Floatation-REST has an impact on anxiety, emotional distress, eating disorder severity, functional ability, and interoception.

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
Female
Target Recruitment
68
Inclusion Criteria
  • Primary clinical diagnosis of anorexia nervosa
  • Receiving inpatient treatment for eating disorder
  • Body mass index greater than or equal to 16
  • No new medication prescription in the week prior to study randomization
  • Independently ambulatory
  • No current evidence of orthostatic hypotension
  • Ability to lay flat comfortably
  • Possession of a smartphone with data plan
  • English proficiency
Exclusion Criteria
  • Active suicidal ideation
  • Active cutting or skin lacerating behaviors
  • Orthostatic hypotension (defined as a drop of ≥ 20 mm Hg in systolic BP or a drop of ≥ 10 mm Hg in diastolic BP when measured shortly after transitioning from lying down to standing)
  • Comorbid schizophrenia spectrum or other psychotic disorder

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Floatation-RESTFloatation-REST plus usual careParticipants will float supine in a pool of water saturated with epsom salt, in a light and sound attenuated chamber, for up to 60 minutes, on 8 separate occasions. Ratings of the experience will be collected before and after each float.
Usual careUsual careParticipants will be assessed along the same time periods, i.e., before and after a 60 minute window, on 8 separate occasions. Ratings of the experience will be collected before and after each time period.
Primary Outcome Measures
NameTimeMethod
Body image dissatisfaction score on the Photographic Figure Rating ScaleThrough study completion, an average of 1 year

Average of the absolute change in body image dissatisfaction from pre to post float across all eight floats (score range: 0 to 10; larger changes indicate greater severity of body image dissatisfaction)

Secondary Outcome Measures
NameTimeMethod
Functional ability on the Sheehan Disability QuestionnaireThrough study completion, an average of 1 year

Change in functional ability after the final float relative to baseline (range 0 to 30, higher scores indicate greater severity of disability)

Anxiety on the Spielberger State Trait Anxiety InventoryThrough study completion, an average of 1 year

Average of the change in anxiety rating from pre to post float across all eight float (range 20 to 80, higher scores indicate greater severity of anxiety)

Interoceptive self report on the Multidimensional Interoceptive Awareness ScaleThrough study completion, an average of 1 year

Change in total interoceptive awareness score after the final float relative to baseline (range 0 to 160, higher scores indicating greater interoceptive awareness)

Body image disturbance on the Body Appreciation Scale-2Through study completion, an average of 1 year

Change in body image disturbance score after the final float relative to baseline (range 10 to 50, higher scores indicating reduced severity of body image disturbance)

Eating disorder severity on the Eating Disorder Examination QuestionnaireThrough study completion, an average of 1 year

Change in eating disorder severity after the final float relative to baseline (range 0 to 6, larger scores indicate greater severity of eating disorder)

Body image disturbance on the Body Image States ScaleThrough study completion, an average of 1 year

Change in body image disturbance after the final float relative to baseline (range 0 to 48, higher scores indicate greater severity of body image disturbance)

Anxiety on the NIH Promis Anxiety ScaleThrough study completion, an average of 1 year

Average of the change in anxiety rating from pre to post float across all eight float (range 6 to 30, higher scores indicate greater severity of anxiety)

Anxiety sensitivity on the Anxiety Sensitivity Index-3RThrough study completion, an average of 1 year

Change in anxiety sensitivity after the final float relative to baseline (range 0 to 96, higher scores indicate greater severity of anxiety sensitivity)

Trial Locations

Locations (1)

Laureate Institute for Brain Research

🇺🇸

Tulsa, Oklahoma, United States

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