IRCT20100513003922N4
Recruiting
Phase 1
Comparing the effectiveness of olive leaf extract and Pregabalin on symptomatic treatment of diabetic neuropathy
Overview
- Phase
- Phase 1
- Status
- Recruiting
- Enrollment
- 66
Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18 years to no limit (—)
- Sex
- All
Inclusion Criteria
- •Type I and II diabetic patients who have diabetes for at least one year and have diabetic neuropathy pain
- •History of neuropathic pain for at least three months
- •a pain score (VSA) equal to or greater than 4
- •at least 18 years of age or older
- •HbA1c is equal to or less than 11
Exclusion Criteria
- •Pregnant and lactating women
- •ischemic pain or other pain such as pains associated with amputation or arthritis
- •Electroconvulsive Therapy in the past 30 days
- •using warfarin, antiarrhythmic drugs, sedatives, hypnotices, anticonvulsants, NSAIDs and capsaicin in the past 7 days
- •using antipsychotics, antidepressants, opioids and muscle relaxants during the past 14 days
- •using anti\-neuropathic drug and Unwillingness to stop taking it
- •Dependence on alcohol or other drugs
- •important metabolic diseases, cardiovascular diseases, thyroid disease, major blood diseases, reduced kidney function or liver function, bipolar disease, psychosis
- •history of suicide
- •drug sensitivity
Investigators
Similar Trials
Terminated
Phase 4
Effect of an Olive Leaf Extract compared to a placebo on Cold and Flu Symptoms in an AdultPopulation – A double blind, randomised controlled trialCommon ColdInfluenza virus infectionAlternative and Complementary Medicine - Herbal remediesInfection - Other infectious diseasesACTRN12619001722189Pharmactive135
Recruiting
Not Applicable
Effects of a combination of olive leaf extract and potassium on blood pressure in subjects with mild to moderate hypertension - a doubleblind, randomized, placebocontrolled studyMild to moderately elevated blood pressure (high normal and hypertension grade 1)DRKS00031955APOMEDICA Pharmazeutische Produkte GmbH70
Completed
Not Applicable
The effect of olive leaf extract administration on cardiovascular healthRisicofactoren voor cardiovasculaire ziekten(borderline) hypercholesterolemiahigh cholesteroloverweightobesityNL-OMON44077niversiteit Maastricht80
Completed
Phase 2
Olive (Olea europaea) leaf extract on blood pressureEssential hypertension.Hypertensive diseasesIRCT2017043033730N1Vice Chancellor for research of Qazvin University of Medical Sciences60
Completed
Phase 2
The effect of topical olive leaf extract 2% and topical acyclovir 5% on facial herpes simplexherpes simplex facialis.Herpesviral vesicular dermatitisIRCT138808092652N1orestan University of Medical Sciences62