The effects of stress on involuntary memories

• Conditions: traumatic stress; posttraumatic stress disorder

• Registration Number: NL-OMON28787
• Lead Sponsor: Academic Medical Center

Brief Summary

A

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 68

Inclusion Criteria

Male sex;

- Age 18-40 years;

Exclusion Criteria

- Current major medical disorder;

- Current use of medications known to impact ANS and HPA axis function;

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Differences between stressor and control condition in: salivary cortisol and alpha amylase output as measured six times during the experimental paradigm and the total frequency of intrusive memories during the 7 days following the experimental paradigm.

Secondary Outcome Measures

Name	Time	Method
- Differences between stressor and control condition in accuracy of voluntary memory and characteristics of intrusive memories related to the trauma film.<br /><br>- Associations between baseline glucocorticoid receptor functioning, cortisol and alpha amylase stress reactivity during the experimental paradigm and voluntary memory accuracy and intrusive memory frequency and characteristics.