Neuromechanical Characterization of Agonist and Antagonist Muscle Activations in the Lower Limbs During Walking After Central Nervous System Injury
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Stroke
- Sponsor
- Henri Mondor University Hospital
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Coefficient of antagonist activation
- Status
- Not Yet Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
The retrospective study investigates the part of responsibility of neuromuscular disorders associated with chronic hemiparesis in walking impairment.
Detailed Description
After injury to the central nervous system, walking disorders are associated with complex neuromuscular mechanisms that alter the direction and intensity of the descending control, reflex reactions to kinematic changes and the mechanical components of soft tissues. The dissociated analysis of these mechanisms and their interactions during multi-segmental movements and especially during walking is poorly described. However, a quantified assessment of the responsibility of each of the neuromuscular mechanisms in the functional disorder would guide the choice of treatments. 3D gait laboratories provide kinematic data from synchronized walking to surface electromyograms as part of additional assessments to assist in the follow-up of patients with chronic hemiparesis. Retrospective analysis of these data would help to better characterize muscular activation disorders and passive resistance to movement during walking in this population.
Investigators
Emilie Hutin
Director
Henri Mondor University Hospital
Eligibility Criteria
Inclusion Criteria
- •Person who performed tridimensional gait analysis in laboratory
- •Person who had a stroke at least 6 months before the gait analysis
Exclusion Criteria
- •Any other neurological pathology or gait disorders
- •Botulinum toxin injection in the last 3 months before the gait analysis
Outcomes
Primary Outcomes
Coefficient of antagonist activation
Time Frame: 1 year
The coefficient of antagonist activation of gastrocnemius medialis and soleus was calculated from EMG data by the ratio between the root mean square amplitude during antagonist effort and maximal agonist effort for the same muscle.