Double Pet Project : A Comparison Between 11C-Acetate and 11C-acetoacetate Heart and
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 2
- 主要终点
- Mean in left ventricule myocradial blood flow
研究概览
简要总结
The objective of this study is to make a comparison between 11C-acetate and 11C-Acetoacetate heart and kidney metabolism
详细描述
Healthy people will have two positron emission tomography scan to perform. One, with a 11C-Acetate Tracer and the other with 11C-Acetoacetate. The results will allow to determine if both tracers are used in a similar way but the organs and see if the investigators can use the already validated analyse method for acetate to make acetoacetate analysis
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Sequential
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Aged between 18 and 55
- •BMI between 18,5 and 28
- •Normal value for blood pressure
排除标准
- •Taking drugs that could influence metabolism
- •Diabetes or prediabetes
- •Pregnancy or lactation
- •Participation in a intensive sport program
- •Being on a ketogenic diet
- •Any clinical abnomally in prescreen blood sample
结局指标
主要结局
Mean in left ventricule myocradial blood flow
时间窗: 30 minutes
Heart acetate metabolism measured by TEP scan
Mean in left ventricule myocardial blood flow
时间窗: 30 minutes
Heart acetoacetate metabolism measured by TEP scan
Mean in Kidney acetoacetate uptake
时间窗: 30 minutes
Kidney acetoacetate uptake measured by TEP scan.
Mean in Kidney acetate uptake
时间窗: 30 minutes
Kidney acetate uptake measured by TEP scan
次要结局
未报告次要终点