Study by Magnetic Resonance Imaging in the Progressive Forms of Multiple Sclerosis
- Conditions
- Progressive Multiple SclerosisMultiple Sclerosis, Relapsing-Remitting
- Registration Number
- NCT02580669
- Lead Sponsor
- University Hospital, Montpellier
- Brief Summary
The goal of this study is to show pattern differences of vasoreactivity and connectivity between Progressive Multiple Sclerosis and Relapsing Remitting Multiple Sclerosis, by the use of methods of advanced brain MRIs and the Diffusion Tensor Imaging , and correlate these differences with Clinical disability and cognitive disorder results.
- Detailed Description
The goal of this study is to show pattern differences of vasoreactivity and connectivity between Progressive Multiple Sclerosis and Relapsing Remitting Multiple Sclerosis, by the use of methods of advanced brain MRIs, and correlate these differences with Clinical disability and cognitive disorder results. The modification of the Diffusion Tensor Imaging are well known in these two groups, as well as their link with the occurrence of movement and cognitive disorder. The study of the vasoreactivity during MRI aims to confront our results to the available data sources.
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 70
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Cerebral vasoreactivity measured by diffusion imaging MRI (quantitative variable) :parameter which allow us to estimate the organization of the white matter tracts 2 months
- Secondary Outcome Measures
Name Time Method Comparison of fonctional connective cards at Resting state 2 months somatomotor network and default mode network
Cognitive disorders 2 months Neuropsychological test results (quantitative and quantitative variable)
Trial Locations
- Locations (1)
Hopital Gui de Chauliac -Service de Neurologie
🇫🇷Montpellier, France
Hopital Gui de Chauliac -Service de Neurologie🇫🇷Montpellier, France