Assessment of Neural Inspiratory Time Through Transesophageal and Surface Electromyography
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- the onset and duration of neural inspiratory time
研究概览
简要总结
The onset and offset of the neural inspiratory time are fundamentally important measurements in studies of patientventilator interaction, where the level of assistance delivered by the ventilator is controlled by the patient's demand. The onset of neural inspiratory time can be determined in esophageal pressure, transdiaphragmatic pressure, and EMG signals. The investigator compare the onset measured by EMG, esophageal and transdiaphragmatic pressure, and consider that the correlation between them is well in different conditions.
详细描述
The onset and offset of the neural inspiratory time are fundamentally important measurements in studies of patien-tventilator interaction, where the level of assistance delivered by the ventilator is controlled by the patient's demand. Patient-ventilator asynchrony evaluated using the time lag between onset of the neural inspiratory time and the onset of a mechanical ventilation signal. The onset of neural inspiratory time can be determined in esophageal pressure, transdiaphragmatic pressure, and EMG signals. The investigator compare the onset measured by EMG, esophageal and transdiaphragmatic pressure, and consider that the correlation between them is well in three different conditions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •normal cardio-pulmonary function
- •without low inspiratory muscle strength
- •non-smoker
- •without history of the nervous system and respiratory system disease
- •sever to very severe stable stage
排除标准
- •systemic application of corticosteroids nearly 4 weeks
结局指标
主要结局
the onset and duration of neural inspiratory time
时间窗: through study completion, an average of 5 hours
Correlation between onsets and duration of measured from espphageal pressure, transdiaphragmatie pressure and EMG.
次要结局
未报告次要终点
研究者
Zhenfeng He
principal investigator
Guangzhou Medical University
