Does ketamine improve the quality of sedation of intranasal dexmedetomidine premedication in childre

Phase 3

Completed

• Conditions: Tonsillitis; Respiratory - Other respiratory disorders / diseases

• Registration Number: ACTRN12616001522404
• Lead Sponsor: Yusheng Yao

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-11-04
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 66

Inclusion Criteria

Children were engaged in this study, who were with American Society of Anesthesiologists (ASA) physical status I or II, aged between 3 and 7 years old and scheduled to undergo elective tonsillectomy.

Exclusion Criteria

Children were excluded from the study if they had significant renal or hepatic disorders, dysrhythmias, recent upper respiratory infection, asthma, nasal pathology, allergy or hypersensitive reaction to dexmedetomidine or ketamine, therapy of opioid or non-steroidal anti-inflammatory drug in the 24 hours prior to the study, and a medical history of mental illness.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sedation state will be evaluated by Modified Observer’s Assessment of Alertness/Sedation Scale(MOAA/S).[Sedation state will be evaluated at 30min after premedication.]