Effectiveness of Telemedicine Use in Home Management of Adult Egyptian Mild COVID-19 Cases
试验速览
- 阶段
- 不适用
- 入组人数
- 400
- 试验地点
- 1
- 主要终点
- Percent of adherence to isolation measures
研究概览
简要总结
Keeping in mind the rising number of cases in Egypt and the strain they put on hospital infrastructure, the idea of home isolation and follow up for COVID 19 positive cases has been adopted in many countries and was approved by World Health Organization (WHO) and Egyptian Ministry of health (MOH).
Telehealth can help to mitigate this risk by minimizing the amount of face-to-face interactions. The WHO mentioned telemedicine among essential services in "strengthening the Health Systems Response to COVID-19" policy. The aim in this study is to study the effectiveness of telemedicine in managing mild COVID cases regarding isolation measures, symptoms, medications adherence, and reporting of red flags and side effects.
详细描述
Objectives:
- To assess the effectiveness of follow up of mild COVID-19 cases in home isolation
- To assess the applicability of telemedicine tools in the follow up of those patients and early identification of warning symptoms needing more intensive management measures.
- To assess the clinical characteristics for mild COVID-19 cases and post covid sequelae and the course of symptoms
- To assess the persistence of symptoms during follow up.
- To assess the quality of life during home management period.
- To assess cost-effectivenes of home isolation vs hospital admission in mild COVID-19 cases.
Study population & Sample size :
The study includes 400 Adult (18-65 years) Egyptian patients with mild COVID 19 diagnosed by PCR consented (oral consent) to home isolation to follow them.
Study Design:
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •No co-morbidities that necessitates hospital admission due to high risk for progression of the disease: Pregnancy, uncontrolled Diabetes, Chronic lung disease, Chronic kidney disease, Chronic liver disease, Serious heart diseases (arrythmia, Ischemic heart disease, uncontrolled hypertension), immunocompromised: prolonged use of corticosteroids and other immunosuppressive drugs/ organ transplantation/ HIV/ Immunodeficiency.
- •No fever (oral, below or equal 37.50 C )
- •No shortness of breath (Respiratory rate 12-20/min)
- •Oxygen saturation >= 96 %
- •CT chest: Normal
- •Labs: D-dimer<1000ng/ml, CPK< twice upper limit of normal, CRP<100, LDH<245, Ferritin<500, absolute lymphocytic count >0.8
排除标准
- •Moderate and severe cases not fulfilling the definition of mild cases.
- •Children and young < 18 years.
- •Age >65 years.
- •Presence of any of the previously mentioned comorbidities.
结局指标
主要结局
Percent of adherence to isolation measures
时间窗: 3-6 months
A checklist to check the percent of the patients who followed the advices for home isolation and will be validated
The incidence of symptoms and their duration
时间窗: 3-6 months
days
次要结局
- Change in Short Form 35 (SF-36) Questionnaire(3-6 months)
- Cost- effectiveness of Home Isolation vs hospital admission in mild COVID-19 cases(3-6 months)
- Identifying the duration of post-COVID-19 symptoms(3-6 months)
- long-term respiratory complications(3-6 months)
研究者
Mohamed Tharwat Hegazy
Lecturer of Internal Medicine, Rheumatology and Clinical Immunology
Cairo University