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Clinical Trials/TCTR20190703002
TCTR20190703002
Recruiting
未知

A randomized control trial comparing high flow oxygen therapy with low level pressure support during spontaneous breathing trial

Faculty of Medicine Siriraj Hospital, Mahidol University0 sites330 target enrollmentJuly 3, 2019
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Overview

Phase
未知
Intervention
Not specified
Conditions
&#45
Sponsor
Faculty of Medicine Siriraj Hospital, Mahidol University
Enrollment
330
Status
Recruiting
Last Updated
last year
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
July 3, 2019
End Date
August 31, 2020
Last Updated
last year
Study Type
Interventional
Sex
All

Investigators

Sponsor
Faculty of Medicine Siriraj Hospital, Mahidol University

Eligibility Criteria

Inclusion Criteria

  • •1\. Age 18\-90 years
  • •2\. On mechanical ventilation for at least 24 hours
  • •3\. Ready to wean by the following criteria
  • •\- FiO2 \< 0\.5
  • •\- Positive end expiratory pressure \< 8 cmH2O
  • •\- PaO2/FiO2 \> 200 หรือ SpO2 \> 92%
  • •\- Respiratory rate \< 30/min
  • •\- Stable hemodynamic (without or receiving norepinephrine less than 0\.05 mcg/kg/min)
  • •\- Well cooperate
  • •4\. Agree to participate

Exclusion Criteria

  • •1\. Unstable hemodynamics: at least one of the following criteria
  • •\- SBP \> 180 or \< 90 mmHg
  • •\- DBP \> 120 or \< 60 mmHg
  • •\- Heart rate \> 140 or \< 60/min
  • •\- Presence of shock or poor tissue perfusion
  • •2\. Severe acid\-base disturbance: pH \< 7\.3 or \> 7\.55
  • •3\. Pregnant women
  • •4\. Trachostomized patients

Outcomes

Primary Outcomes

Not specified

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