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临床试验/TCTR20190703002
TCTR20190703002招募中未知

A randomized control trial comparing high flow oxygen therapy with low level pressure support during spontaneous breathing trial

Faculty of Medicine Siriraj Hospital, Mahidol University0 个研究点目标入组 330 人开始时间: 2019年7月3日最近更新:
适应症

试验速览

阶段
未知
状态
招募中
发起方
入组人数
330

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 Years 至 90 Years(—)
性别
All

入选标准

  • 1. Age 18-90 years
  • 2. On mechanical ventilation for at least 24 hours
  • 3. Ready to wean by the following criteria
  • - FiO2 < 0.5
  • - Positive end expiratory pressure < 8 cmH2O
  • - PaO2/FiO2 > 200 หรือ SpO2 > 92%
  • - Respiratory rate < 30/min
  • - Stable hemodynamic (without or receiving norepinephrine less than 0.05 mcg/kg/min)
  • - Well cooperate
  • 4. Agree to participate

排除标准

  • 1. Unstable hemodynamics: at least one of the following criteria
  • - SBP > 180 or < 90 mmHg
  • - DBP > 120 or < 60 mmHg
  • - Heart rate > 140 or < 60/min
  • - Presence of shock or poor tissue perfusion
  • 2. Severe acid-base disturbance: pH < 7.3 or > 7.55
  • 3. Pregnant women
  • 4. Trachostomized patients

研究者

发起方
Faculty of Medicine Siriraj Hospital&#44; Mahidol University

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