Study of Iron Accumulation Measured in MRI in Non-pathological Aging

Recruiting

• Conditions: Healthy Aging

• Registration Number: NCT04659824
• Lead Sponsor: University Hospital, Lille

Brief Summary

To study the correlation between the iron load in brain, measured in MRI, and the age of healthy subjects Secondary objectives are to study the correlations between the iron load in cortical brain regions and (i) the cognitive performances, (ii) markers of aging (MRI, EEG, OCT, biology),and (iii) demographical factors involved in iron load.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-12-02
• Study First Submitted QC: 2020-12-02
• Study First Posted: 2020-12-09
• Status Verified: 2023-01
• Study Start: 2023-01-30
• Last Update Submitted: 2023-02-02
• Last Update Posted: 2023-02-06
• Primary Completion: 2025-01
• Study Completion: 2025-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 190

Inclusion Criteria

• Men or women between 18 and 95 years old
• French speaker with capability to understand the instructions
• Health insurance

Exclusion Criteria

• Pregnancy
• minor subject
• no informed consent agreement
• subject enrolled in pharmaceutic study or exclusion period
• MRI contra-indications
• Neurological or psychiatric disorders
• MOCA < 26
• Psychotropic drugs
• More than 3 MRI exams
• More than 1 neuropsychological assessment (same cognitive tests) in the last 12 months
• Unable to follow the entire protocol according to the investigator

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Correlation coefficient between iron load in MRI and age	baseline

Trial Locations

Locations (1)

Hopital Roger Salengro, CHU Lille; 🇫🇷 Lille, France