Early dynamic screening for colorectal cancer via novel protein biomarkers reflecting biological initiation mechanisms (DIOPTRA)

Centre Hospitalier Universitaire de Liège0 sites1,900 target enrollmentOctober 26, 2023

Overview

No summary available.

Registry

who.int

Start Date

October 26, 2023

End Date

December 31, 2026

Last Updated

2 years ago

Study Type

Observational

Sex

All

Sponsor

•Inclusion criteria for prospective data collection and pilot evaluation:
•1\. Any indication for total colonoscopy (including routine screening and presence of symptoms/FIT positive)
•2\. Age 18\-80 years at the moment of recruitment (see above)
•3\. Absence of significant comorbidities (American Society of Anesthesiologists \[ASA] IV)
•4\. Ability to provide valid (written informed) consent
•Inclusion criteria for the follow\-up study patients who will use the DIOPTRA mobile application:
•1\. Presenting the four inclusion criteria above
•2\. Patients willing to use the DIOPTRA application regularly
•3\. Level of digital literacy allowing to manage mobile terminals (smartphones, smartphone apps, tablets)
•4\. Good coverage of internet connection at home

•Persons belonging to the vulnerable group will not be included in the clinical study
•Other exclusion criteria for the prospective study:
•1\. Age under 18 or above 80 years old
•2\. Comorbidities ASA IV
•3\. Recent major abdominal surgery (colectomy) or radiation prior to the recruitment
•4\. Inflammatory bowel diseases
•5\. Polyposis syndrome
•6\. Pregnancy or suspicion of pregnancy
•7\. Colorectal cancer history
•8\. Not able to understand the study and provide valid consent