Early dynamic screening for colorectal cancer via novel protein biomarkers reflecting biological initiation mechanisms (DIOPTRA)

Centre Hospitalier Universitaire de Liège0 个研究点目标入组 1,900 人开始时间: 2023年10月26日最近更新: 2023年12月12日

适应症

试验速览

暂无简介。

•Inclusion criteria for prospective data collection and pilot evaluation:
•1. Any indication for total colonoscopy (including routine screening and presence of symptoms/FIT positive)
•2. Age 18-80 years at the moment of recruitment (see above)
•3. Absence of significant comorbidities (American Society of Anesthesiologists [ASA] IV)
•4. Ability to provide valid (written informed) consent
•Inclusion criteria for the follow-up study patients who will use the DIOPTRA mobile application:
•1. Presenting the four inclusion criteria above
•2. Patients willing to use the DIOPTRA application regularly
•3. Level of digital literacy allowing to manage mobile terminals (smartphones, smartphone apps, tablets)
•4. Good coverage of internet connection at home
•5. Availability of a smartphone/tablet (in order to be able to use the app)
•6. Belonging to the healthy or non-advanced adenoma groups

•Persons belonging to the vulnerable group will not be included in the clinical study
•Other exclusion criteria for the prospective study:
•1. Age under 18 or above 80 years old
•2. Comorbidities ASA IV
•3. Recent major abdominal surgery (colectomy) or radiation prior to the recruitment
•4. Inflammatory bowel diseases
•5. Polyposis syndrome
•6. Pregnancy or suspicion of pregnancy
•7. Colorectal cancer history
•8. Not able to understand the study and provide valid consent
•Exclusion criteria for the follow-up study:
•1. Classification in the CRC or advanced adenoma groups
•2. Non-availability of a smartphone/tablet or inability to use a mobile app (e.g., due to low digital literacy)

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