ano-Tacrolimus and Cyclosporine effect in dry eye

Phase 3

• Conditions: Dry eye syndrome.; Other disorders of lacrimal gland; H04.1

• Registration Number: IRCT20181006041253N1
• Lead Sponsor: Birjand University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 June 2021

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

chronic symptoms of burning, foreign body sensation or itching in both eyes, blurring of vision, photo phobia,and pain
daily need for artificial tears
The ocular surface disease index (OSDI)=23
tear film break-up time (TBUT) value of 10s or lower
Strip Meniscometry test (SM tube) = 10 mm
Schirmer test value at 5 min of 10mm or lower

Exclusion Criteria

Sensitivity to tacrolimus
Pregnancy or lactation
Other systemic atopic diseases
Previous eye surgery
Any structural abnormalities (lid scarring, entropion, trichiasis, etc.)
Any inflammation in the anterior chamber
Glaucoma
Use of other topical drugs, other than artificial tears
Use of topical or systemic antibiotics or anti-inflammatory drugs before entering the study
Contact lens
punctual occlusion

Study & Design

• Study Type: interventional
• Study Design: Not specified