CTRI/2020/05/025319招募中3 期
Angiotensin Receptor Blocker Losartan for prevention of COVID 19 complications: a randomized placebo controlled trial - LICCI
试验速览
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. Age > 18 years
- •2. Requirement of hospitalization
- •3. Randomization within 24 hours of initial presentation to a hospital/diagnosis
排除标准
- •1. Currently taking an angiotensin converting enzyme inhibitor (ACEi) or Angiotensin receptor blocker (ARB)
- •2. Prior reaction or intolerance to an ARB or ACEi
- •3. Blood pressure less than 100/70 mmHg
- •4. Potassium great than 5.0 mEq/L
- •5. Pregnancy or breastfeeding In females of childbearing age, unwillingness to use birth control for the duration of the study
- •6. Estimated Glomerular Filtration Rate (eGFR) of < 30ml/min/1.73 m2
- •7. AST and/or ALT > 3 times the upper limit of normal
- •8. Severe volume depletion or severe acute kidney injury that, in the opinion of the investigator, would preclude administration of Losartan
- •9. Concurrent treatment
- •10. Inability to obtain informed consent
- •11. Pregnancy
研究者
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