Assessing Mindfulness Training as a Mechanistic Probe for Stress-Induced Brain Activation and Relapse Prevention for Tobacco Addiction

Yale University1 site in 1 country42 target enrollmentFebruary 2009

ConditionsCigarette Smoking Tobacco Smoking Nicotine Dependence Smoking Cessation

Overview

Phase: N/A
Intervention: Not specified
Conditions: Cigarette Smoking
Sponsor: Yale University
Enrollment: 42
Locations: 1
Primary Endpoint: Between group differences in continuous abstinence
Status: Completed
Last Updated: 9 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to assess the effects of mindfulness training (MT) compared to standard Smoking Cessation Therapy (SCT) on smoking cessation and stress provocation in individuals trying to quit smoking.

Registry

clinicaltrials.gov

Start Date

February 2009

End Date

February 2013

Last Updated

9 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

Yale University

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Between the ages of 18 and 60
•Smoking 10 or more cigarettes per day
•Fewer than 3 months of smoking abstinence in the past year
•Motivated to stop smoking

Exclusion Criteria

•Current use of psychoactive medications that have not been at a stable dose for the past six months, are used as mood stabilizers, or are used as smoking cessation treatments. Individuals who are on psychoactive medications that are stable, not mood stabilizers, and not used for smoking cessations are excluded from fMRI sessions but not smoking cessation treatment.
•Use of another investigational drug within 30 days
•Any serious or unstable disease within 6 months
•Meets criteria for substance dependence within the past year
•Left handed (will be excluded from fMRI only)