Predisposing factors and clinical impact of high-output syndrome after sphincter-preserving surgery with covering ileostomy for rectal cancer: A retrospective single-center cohort study
Not Applicable
- Conditions
- Rectal cancer
- Registration Number
- JPRN-UMIN000040558
- Lead Sponsor
- Cancer Institute Hospital of the Japanese Foundation for Cancer Research
- Brief Summary
High-output syndrome developed in 44/195 eligible patients (22.6%).Multivariable analysis revealed that neoadjuvant(chemo)radiotherapy, postoperative complications, postoperative maximal white blood cell, and postoperative maximal C-reactive protein 10 mgdl were independently associated with high-output syndrome. High-output syndrome was associated with increased renal dysfunction at the time of ostomy closure, but not with nutritional imbalance or electrolyte abnormalities.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 195
Inclusion Criteria
Not provided
Exclusion Criteria
lack of ostomy closure, emergent surgery, lack of laboratory data before ostomy closure
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method