effect of aspirin on permanent Internal Jugular dialysis catheter patency

Phase 3

Conditions: end stage renal disease (ESRD) , patency of internal jugular permcath , aspirin consumption.
Encounter for adjustment and management of vascular access device
Z45.2

Registration Number: IRCT20220110053680N1

Lead Sponsor: Zanjan University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 84

Inclusion Criteria

The patient has ESRD and Glomerular Filtration Rate (GFR) <15ml / min / 1.73 m^2.
At least one month should be passed since the start of hemodialysis maintenance.
At least one month and at most one year should be passed since the installation of the internal jugular permcath .
There shouldn't have any definitive contraindication for normal use of aspirin

Exclusion Criteria

Current aspirin use at the time of entrance in the study
Presence of a known underlying disease that increases the risk of thrombosis (lupus, antiphospholipid syndrome, presence of nephrotic syndromes)
use of anticoagulants (warfarin, heparin, apixaban, rivaroxaban, plavix)
use of Tarulac
Catheter infection before beginning the study
Incomplete patient document regarding the items required in the study
Patient disfavor with inclusion in the study

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Duration of internal jugular permcath patency. Timepoint: Weekly. Method of measurement: Number of days that permcath has function during the 6 month of the study.

Secondary Outcome Measures

Name	Time	Method
Duration of time that patient has suffered from End Stage Renal Disease (ESRD). Timepoint: At onset of study. Method of measurement: Number of months passed since the diagnosis of ESRD and onset of hemodialysis.;History of heart failure. Timepoint: At onset of the study. Method of measurement: Ejection Fraction (EF) less than 50% according to echocardiography record in patient's file.;Hypertension. Timepoint: At onset of the study and in patients with hypertension, weekly until the end of the study. Method of measurement: Systolic blood pressure (SBP) = 140 mmHg or Diastolic blood pressure (DBP) = 90 mmHg according to patient's file.;Diabetes mellitus. Timepoint: At onset of the study. Method of measurement: Fast Blood Sugar (FBS) = 126 mg/dl according to patient's file.;Age. Timepoint: At onset of the study. Method of measurement: Asking from patient.;Sex. Timepoint: At onset of the study. Method of measurement: Observation.