The Effect of a Natural Polyphenolic Extract From Pomegrnate (POMX) on the Development of Atherosclerosis in Diabetic Patients

Phase 4

• Conditions: Atherosclerosis

• Registration Number: NCT00470808
• Lead Sponsor: HaEmek Medical Center, Israel

Brief Summary

Diabetes is a highly atherogenic disease. Pomegranate juice has impressive antioxidant properties. It has been proven to decrease oxidant stress and to cause the regression of atherosclerotic plaques in hypercholestrolemic and diabetic patients.Furthermore it has been proven to potentiate the biologic activity of the enzyme paraoxonase 1 which is very important in preventing atherosclerosis. The study will try to prove that a polyphenolic extract from pomegranate (POMx) has the same desired effects.

Detailed Description

Not available

Study Timeline

• Status Verified: 2007-04
• Study Start: 2007-05
• Study First Submitted: 2007-05-07
• Study First Submitted QC: 2007-05-07
• Last Update Submitted: 2007-05-07
• Study First Posted: 2007-05-08
• Last Update Posted: 2007-05-08
• Study Completion: 2007-08

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Male
• Target Recruitment: Not specified

Inclusion Criteria

• Males
• HBA1C>7%
• Drug therapy given for DM

Exclusion Criteria

• Age<18
• Inclusion in another study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Trial Locations

Locations (1)

Ha'Emek Medical Center; 🇮🇱 Afula, Israel