TCTR20230428002Unknown不适用
ASSOCIATION OF GUT MICROBIOTA WITH DYSLIPIDEMIA AND CHRONIC CORONARY SYNDROME PATIENTS UNDERGOING CORONARY ANGIOGRAPHY
Faculty of Medicine, Srinakharinwirot University0 个研究点目标入组 117 人开始时间: 2023年4月28日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 117
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 35 Years 至 70 Years（—）
- 性别
- All
入选标准
- •The first group: Healthy volunteers
- •1. Volunteers must be 35-70 years old
- •2. Volunteers must not have any of the following risk factors for cardiovascular disease
- •- Dyslipidemia
- •- Type 2 diabetes mellitus
- •- Hypertension
- •- Metabolic syndrome.
- •3. Volunteers must not have acute coronary syndrome or chronic coronary syndrome
- •4. Volunteers are willing to participate in the research by signing the consent forms
- •The second group: Patients with cardiovascular risk factors, dyslipidemia
- •1. Volunteers must be 35-70 years old
- •2. Volunteers must have a risk factor for cardiovascular disease, dyslipidemia
- •3. Volunteers must not have any of the following risk factors for cardiovascular disease
- •- Type 2 diabetes mellitus
- •- Hypertension
- •- Metabolic syndrome.
- •4. Volunteers are willing to participate in the research by signing the consent forms.
- •The third group: Patients with chronic coronary syndrome undergoing coronary angiography
- •1. Volunteers must be 35-70 years old
- •2. Volunteers with chronic coronary syndrome undergoing coronary angiography
- •Chronic coronary syndrome patients refer to the patients with angina pectoris due to demand-supply mismatch which cause myocardial ischemia. Coronary anatomy is greater than 70% stenosis in coronary arteries that are larger than 2.5 mm in one view of coronary angiogram, greater than 50% stenosis in coronary arteries in more than two views of coronary angiogram and greater than 50% stenosis in the left main coronary artery.
- •3. Volunteers are willing to participate in the research by signing the consent forms
排除标准
- •1. Volunteers with underlying disease including chronic kidney disease (eGFR < 60 ml/min/1.73 m2 for more than 3 months), liver disease (AST/ALT > 5 times normal or jaundice), cancer, intestinal diseases such as inflammatory bowel disease, thyroid dysfunction, immunodeficiency such as human immunodeficiency virus (HIV)
- •2. Volunteers who take antibiotics, immunosuppressants, probiotics supplement, synbiotics, herbal supplements, antacids or laxatives within 4 weeks before participating in the study
- •3. Volunteers who have history of gastrointestinal disease and other infections within 4 weeks
- •4. Volunteers who smoke
- •5. Volunteers with alcoholism
- •6. Volunteers who are pregnant or lactating
- •7. Volunteers who have Covid-19 infection within 4 weeks
- •8. Volunteers who refuse to participate in the research
研究者
相似试验
已完成
不适用
Glycosylation Defects causing DYslipidemiaDyslipidemiacholesterol disturbances1002766410013317NL-OMON38669Academisch Medisch Centrum100
已完成
4 期
Dyslipidemia management by Mustadi Ghana and lifestyle modificatioCTRI/2017/05/008627Institute for Post Graduate Teaching and Research in Ayurveda Gujarat Ayurved University54
招募中
不适用
Investigation of tear film and meibomian gland related parameters in patients with dyslipidemia-multicenter studyDyslipidemiaJPRN-UMIN000036351Itoh Clinic200
已完成
不适用
Analysis of ANGPTL in diabetes with dyslipidemiadiabetesJPRN-UMIN000034317Yokohama City University Medical Center100
已完成
不适用
Study in patients of increased blood cholesterolCTRI/2016/11/007486All India Institute of Medical Sciences AIIMS