跳至主要内容
临床试验/NCT03994640
NCT03994640已完成2 期

Myorelaxant Effect of Cannabis Cream Topical Skin Application in Patients With Temporomandibular Disorders: a Randomized, Double-blind Study

Medical University of Silesia2 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2018年1月1日最近更新:
适应症
干预措施

试验速览

阶段
2 期
状态
已完成
入组人数
20
试验地点
2
主要终点
Reduction of sEMG activity of masseter muscle

研究概览

简要总结

Evaluation of myorelaxant effect of cannabis cream.compared to placebo cream in topical skin application in patients with TMD

详细描述

Cannabis sativa has a very wide application in various fields of medicine. In patients with temporomandibular disorder, especially with myofascial pain of masticatory muscles there is a special need to seek an effective pain therapy and muscle relaxing methods. Patients with TMD suffer from chronic pain and depression, cannabis topical skin application therapy seems promising in that field. Patients attending The Department of TMD in Zabrze, Polska were randomly divided into two groups: experimental and placebo. sEMG activity values were compared during 14 days therapy with cream. Positive results were obtained confirming the efficacy of the cannabis cream used in the study, compared to placebo.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Care Provider)

盲法说明

double blind study: for patients and researchers

入排标准

年龄范围
22 Years 至 27 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

研究组 & 干预措施

Cannabis cream

Experimental

Cannabis cream topical skin application in experimental group

干预措施: Cannabis Cream (Combination Product)

Placebo cream

Placebo Comparator

Placebo cream topical skin application in control group

干预措施: Placebo Cream (Combination Product)

结局指标

主要结局

Reduction of sEMG activity of masseter muscle

时间窗: 14 days

Reduction in masseter muscle electromyographic activity

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Aleksandra Nitecka-Buchta

Principal Investigator

Medical University of Silesia

研究点 (2)

Loading locations...

相似试验