ISRCTN82825745已完成1 期
Study to investigate the association between the response to a cholinergic challenge with galantamine and the clinical response to subsequent treatment with galantamine in patients with mild to moderate Alzheimer’s Disease
适应症
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 50
研究概览
简要总结
2022 Results article in https://pubmed.ncbi.nlm.nih.gov/34964149/ (added 31/10/2022)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Clinical diagnosis of AD
- •2. Mini Mental State Examination (MMSE) score ranging from 18 to 26
- •3. Clinical Dementia Rating (CDR) score between 0.5 and 2.0
排除标准
- •1. Previous or current use of CEIs, anticholinergic drugs or neuroleptics
- •2. Contraindications for the use of CEIs
- •3. Use of benzodiazepines 48 hours prior to the study days
- •4. History of psychiatric disorders
研究者
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