NCT02635087招募中不适用
microRNAs Tool for Stratifying Stage II Colon Cancer:a Perspective Study of Adjuvant Chemotherapy
First Affiliated Hospital, Sun Yat-Sen University1 个研究点 分布在 1 个国家目标入组 630 人开始时间: 2015年12月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 630
- 试验地点
- 1
- 主要终点
- DFS
研究概览
简要总结
The investigators discover the investigators' miRNA tool can be a useful tool to predict the patients with stage II colon who can benefit from chemotherapy.Then the investigators plan to make an observation study that may validation this tool.
详细描述
This is an observation study. The investigators recruit patients who agree to use their postoperative specimen for miRNA tool examination and receive the investigators' follow up.Their receiving chemotherapy or not will decided by their doctors. The investigators just see whether the stratifying tool could predict prognosis.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The informed consent has been obtained from the patient.
- •With confirmed diagnosis of stage II colon cancer.
- •With moderate/good ECOG health rating (PS): 0-1 score.
- •The patient receive no anti-cancer treatment before primary surgery.
- •The patient receive radical operation for colon cancer with negative margin.
排除标准
- •With severe comorbidities, such as cardiovascular disease, chronic obstructive pulmonary disease, diabetes mellitus, and chronic renal dysfunction.
- •With bad compliance or contraindication to enrollment.
- •Pregnant woman or lactating woman.
- •With contraindication to receive adjuvant chemotherapy.
结局指标
主要结局
DFS
时间窗: 3 years
次要结局
- OS(5 years)
研究者
Wu Song
archiater
First Affiliated Hospital, Sun Yat-Sen University
研究点 (1)
Loading locations...
相似试验
招募中
不适用
The Application of DNA Nanomachines for Detecting microRNA in Blood for the Diagnosis of Pancreatic Cancer. Diagnosis of Pancreatic CancerPancreas AdenocarcinomaMicroRNANCT06497777National Taiwan University Hospital30
撤回
不适用
MicroRNAs as Diagnostic and Predictive Biomarkers for Acute Graft Versus Host DiseaseAcute GVH DiseaseNCT02917148Northwell Health
招募中
不适用
The Role of MicroRNA in the Diagnosis, Prognosis and Response to Treatment in Pancreatic CancerPancreatic Cancer Stage IIIPancreatic Cancer Stage IVPancreatic Ductal AdenocarcinomaPancreatic NeoplasmsNCT04406831Nuvance Health200
已完成
不适用
Blood Sample Collection for Experimental Blood Test to Track Liver CancerHepatocellular CarcinomaNCT04720430Thomas Jefferson University7
已完成
不适用
Novel Biophotonics Methodology for Colon Cancer ScreeningColon CancerNCT01999478Boston Medical Center4,000