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Exploring the biological mechanism of Ulcerative Colitis caused by dampness based on cross omics

Not Applicable
Recruiting
Conditions
lcerative colitis
Registration Number
ITMCTR2200005840
Lead Sponsor
Guangdong Provincial Hospital of Traditional Chinese Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

(1) Healthy volunteers with no abnormal clinical manifestations; or those who meet the diagnostic criteria for patients with UC (left colon type, active, mild) dampness pattern and other non-damp syndromes;
(2) Age between 18-70 years old;
(3) Not taking antibiotics, steroids and other hormones, Chinese herbal medicine preparations (including oral and intravenous injection), probiotics such as probiotics or yogurt in the past week;
(4) The patient signed the informed consent and was willing to accept the corresponding examination and treatment.

Exclusion Criteria

(1) Patients with severe heart, liver, kidney and other major organ diseases, hematopoietic system, nervous system or mental diseases;
(2) Combined with other organic diseases of the digestive system (such as peptic ulcer), or systemic diseases that affect the motility of the digestive tract (such as hyperthyroidism, diabetes);
(3) Those who are using or need to continue to use drugs that may affect gastrointestinal function (antidiarrheals, antidepressants, anti-anxiety drugs, intestinal flora regulators, antibiotics, etc.);
(4) Those who have a history of allergy to related drugs used in the study and a history of severe food allergy.

Study & Design

Study Type
Cause/Relative factors study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
metabolomics;Immunomics;genomics;Transcriptomics;
Secondary Outcome Measures
NameTimeMethod
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